Results 1 to 10 of about 1,013,940 (117)
Plagl1 regulates the retinal progenitor cell to Müller glial cell transition. [PDF]
PLoS GeneticsMüller glia arise from late-stage retinal progenitor cells (RPCs) as a distinct lineage that diverges from neurogenic trajectories. Here, we identify the maternally imprinted gene Plagl1 as a key transcriptional regulator of gliogenesis in the murine ...
Yacine Touahri +26 more
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Simvastatin inhibits POVPC-mediated induction of endothelial-to-mesenchymal cell transition [PDF]
Journal of Lipid Research, 2021 Endothelial-to-mesenchymal transition (EndMT), the process by which an endothelial cell (EC) undergoes a series of molecular events that result in a mesenchymal cell phenotype, plays an important role in atherosclerosis.
Yan Li +13 more
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Single cell transcriptomics of human epidermis identifies basal stem cell transition states [PDF]
Nature Communications, 2020 The mechanisms regulating stem cells to give rise to human interfollicular epidermis are unclear. Here, the authors use single cell RNA sequencing to identify heterogeneity within the human neonatal interfollicular epidermis and distinct spatial ...
Shuxiong Wang +11 more
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Biomolecules & Biomedicine, 2021 Long non-coding RNAs are considered to be critical regulators of tumor progression. Tumor protein translationally controlled 1 antisense RNA 1 (TPT1-AS1) was shown to have an oncogenic role in cervical and ovarian cancer.
Jun Tang +6 more
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Zfp281 Inhibits the Pluripotent-to-Totipotent State Transition in Mouse Embryonic Stem Cells
Frontiers in Cell and Developmental Biology, 2022 The cell-fate transition between pluripotent and totipotent states determines embryonic development and the first cell-lineage segregation. However, limited by the scarcity of totipotent embryos, regulators on this transition remain largely elusive.
Xinpeng Wen +7 more
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The liver fluke Opisthorchis felineus as a group III or group I carcinogen
4 open, 2019 Opisthorchiasis caused by the liver fluke Opisthorchis felineus is one of the most common helminthic infections in the Russian Federation. The largest area affected by opisthorchiasis felinea occupies almost the entire territory of Western Siberia and ...
Pakharukova Mariya Yurievna +2 more
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Undervalued ubiquitous proteins
4 open, 2019 The role of ubiquitous proteins (UPs) and their corresponding enzymes have been underestimated in carcinogenesis as the focus of much research revolved around measuring mutations and/or other genetic epiphenomena as surrogate markers of cancer and cancer
Brücher Björn L.D.M., Jamall Ijaz S.
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Microbiome and morbid obesity increase pathogenic stimulus diversity
4 open, 2019 The microbiome, the relationship between environmental factors, a high-fat diet, morbid obesity, and host response have been associated with cancer, only a small fraction of which (
Brücher Björn L.D.M., Jamall Ijaz S.
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MiR-146b-5p/SEMA3G regulates epithelial-mesenchymal transition in clear cell renal cell carcinoma
Cell Division, 2023 Objective The primary purpose was to unveil how the miR-146b-5p/SEMA3G axis works in clear cell renal cell carcinoma (ccRCC). Methods ccRCC dataset was acquired from TCGA database, and target miRNA to be studied was further analyzed using survival ...
Mengxi Tang, Tao Xiong
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Precancerous niche (PCN), a product of fibrosis with remodeling by incessant chronic inflammation
4 open, 2019 Fibroblasts are actively involved in the creation of the stroma and the extracellular matrix which are important for cell adhesion, cell–cell communication, and tissue metabolism.
Brücher Björn L.D.M., Jamall Ijaz S.
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