Results 41 to 50 of about 18,554 (188)

Proteomic and gene expression patterns of keratoconus

Indian Journal of Ophthalmology, 2013
Keratoconus is a progressive corneal thinning disease associated with significant tissue remodeling activities and activation of a variety of signaling networks.
Arkasubhra Ghosh, Lei Zhou, Anuprita Ghosh, Rohit Shetty, Roger Beuerman   +4 more
doaj   +1 more source

Investigating Associations Between Signal Intensity of Silent MR Angiography and Hemodynamic Information From 4D Flow MRI in Brain Arteriovenous Malformation

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Whether signal intensity (SI) on Silent MRA reflects hemodynamics in brain arteriovenous malformations (BAVMs) is unclear. Objectives To evaluate the relationship between Silent MRA SI and 4D flow‐derived hemodynamic parameters and examine whether Silent MRA‐based metrics are associated with symptomatic hemorrhage in BAVM.
Linshu Yang, Xiaosheng Meng, Haining Wei, Xiaoqian Li, Yang Yu, Qin Qin, Dan Zhu, Tao Hong, Hongqi Zhang, Rui Li, Jiaxing Yu, Chunxue Wu, Jie Lu   +12 more
wiley   +1 more source

Management of pediatric keratoconus - Evolving role of corneal collagen cross-linking: An update

Indian Journal of Ophthalmology, 2013
Pediatric keratoconus demonstrates several distinctive management issues in comparison with adult keratoconus with respect to under-diagnosis, poor compliance and modifications in treatment patterns.
Vardhaman P Kankariya, George D Kymionis, Vasilios F Diakonis, Sonia H Yoo   +3 more
doaj   +1 more source

Digital Image Processing and Development of Machine Learning Models for the Discrimination of Corneal Pathology: An Experimental Model

Photonics, 2021
Machine learning (ML) has an impressive capacity to learn and analyze a large volume of data. This study aimed to train different algorithms to discriminate between healthy and pathologic corneal images by evaluating digitally processed spectral-domain ...
Andres Bustamante-Arias, Abbas Cheddad, Julio Cesar Jimenez-Perez, Alejandro Rodriguez-Garcia   +3 more
doaj   +1 more source

Telangiectasia in Systemic Sclerosis Is a Marker of Increased Disease Morbidity and Mortality: Analyses From the Australian Scleroderma Cohort Study

Australasian Journal of Dermatology, EarlyView.
ABSTRACT This Australian retrospective cohort analysis of 1977 patients investigates and expands on correlates of telangiectasia in systemic sclerosis to determine whether this cutaneous sign is a potential surrogate marker for disease progression and prognosis.
Vivien Wai Yun Lai, Dylan Hansen, Maryam Tabesh, Jessica Fairley, Laura Ross, Nava Ferdowsi, Gene‐Siew Ngian, Diane Apostolopoulos, Joanne Sahhar, Lauren V. Host, Jennifer Walker, Gabor Major, Susanna Proudman, Wendy Stevens, Mandana Nikpour, Amanda M. Saracino   +15 more
wiley   +1 more source

Keratoconus: A biomechanical perspective on loss of corneal stiffness

Indian Journal of Ophthalmology, 2013
Keratoconus (KC) is progressive disease of corneal thinning, steepening and collagen degradation. Biomechanics of the cornea is maintained by the intricate collagen network, which is responsible for its unique shape and function.
Abhijit Sinha Roy, Rohit Shetty, Mathew Kurian Kummelil   +2 more
doaj   +1 more source

Decellularised Corneal Stromal Lamina With or Without Autologous Adipose‐Derived Adult Stem Cells for Advanced Keratoconus: 1‐Year Results of a Phase I/IIa Clinical Trial

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To report the 1‐year clinical outcomes of decellularised human corneal stromal lamina implantation, with or without autologous adipose‐derived adult stem cells (ADASCs), for advanced keratoconus in a European cohort. Methods In this prospective, randomised Phase I/IIa trial, 10 eyes of 10 patients were allocated to decellularised ...
Hao Zhang, Jorge L. Alió del Barrio, Alejandra E. Rodriguez, Rafael I. Barraquer, Francisco Arnalich‐Montiel, David Mingo‐Botín, María Eugenia Fernández Santos, Jorge L. Alió   +7 more
wiley   +1 more source

Role of collagen cross linking in keratoconus

MRIMS Journal of Health Sciences, 2017
Background: Corneal grafting is associated inherent risks that could result in permanent loss of vision and significantly affect the quality of life. Corneal collagen cross linking is a new technique that can either prevent corneal transplantation or ...
P V Nanda Kumar Reddy, B V Kranthi
doaj   +1 more source

Surviving Males With PORCN Variants: Expanding the Clinical, Molecular, and Mechanistic Spectrum

Clinical Genetics, EarlyView.
Pathogenic PORCN variants are compatible with male survival in both mosaic and non‐mosaic states, expanding the FDH/PONGOS spectrum and improving diagnosis and genetic counseling. ABSTRACT Pathogenic variants in PORCN cause focal dermal hypoplasia (FDH/Goltz syndrome), an X‐linked dominant disorder historically considered lethal in males, with milder ...
Lucía Miranda‐Alcaraz, Simone Carbonera, Mónica Mora‐Gómez, Natalia Gallego‐Zazo, Inmaculada Guillén, Elena Padilla, Gaia Visani, Alessia Asaro, Valeria Vásquez‐Amell, Mario Cazalla, Manuel Rodríguez‐Canó, Cristina Silván, Pedro Arias, Juan Andrés Jiménez‐Estrada, Tomás Valle, Alejandro Cruz‐Utrilla, Pilar Escribano‐Subías, Nuria Ochoa Parra, María Jesús del Cerro Marín, Julián Nevado, Spanish PAH Consortium, Pablo Lapunzina, Fabio Sirchia, Jair Tenorio‐Castano   +23 more
wiley   +1 more source

Rate of ectasia and incidence of irregular topography in patients with unidentified preoperative risk factors undergoing femtosecond laser-assisted LASIK

Clinical Ophthalmology, 2013
Majid Moshirfar,1 Jared G Smedley,2 Valliammai Muthappan,1 Allison Jarsted,3 Erik M Ostler1 1John A Moran Eye Center, University of Utah, Salt Lake City, UT, USA; 2College of Human Medicine, Michigan State University, Lansing, MI, USA; 3Department of ...
Moshirfar M, Smedley JG, Muthappan V, Jarsted A, Ostler EM   +4 more
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