Results 1 to 10 of about 332,821 (116)

ParSite is a multicolor DNA labeling system that allows for simultaneous imaging of triple genomic loci in living cells. [PDF]

PLoS Biology
The organization of the human genome in space and time is critical for transcriptional regulation and cell fate determination. However, robust methods for tracking genome organization or genomic interactions over time in living cells are lacking.
Xiaohui He, Yadong Sun, Hanhui Ma
doaj   +2 more sources

CRISPR/Pepper-tDeg: A Live Imaging System Enables Non-Repetitive Genomic Locus Analysis With One Single-Guide RNA

Advanced Science
CRISPR‐based genomic‐imaging systems have been utilized for spatiotemporal imaging of the repetitive genomic loci in living cells, but they are still challenged by limited signal‐to‐noise ratio (SNR) at a non‐repetitive genomic locus.
Yuzhi Xu, Zong Dai, Xiaoyong Zou
exaly   +2 more sources

dTAPL, a Method That Expedites the Discovery of Proteins Associated With Specific Genomic Loci in Plants [PDF]

Plant Biotechnology Journal
Liyu Huang, Zhen Zhuang
exaly   +2 more sources

Evolutionary and functional implications of hypervariable loci within the skin virome [PDF]

PeerJ, 2017
Localized genomic variability is crucial for the ongoing conflicts between infectious microbes and their hosts. An understanding of evolutionary and adaptive patterns associated with genomic variability will help guide development of vaccines and ...
Geoffrey D. Hannigan, Qi Zheng, Jacquelyn S. Meisel, Samuel S. Minot, Frederick D. Bushman, Elizabeth A. Grice   +5 more
doaj   +2 more sources

Pgltools: a genomic arithmetic tool suite for manipulation of Hi-C peak and other chromatin interaction data

BMC Bioinformatics, 2017
Background Genomic interaction studies use next-generation sequencing (NGS) to examine the interactions between two loci on the genome, with subsequent bioinformatics analyses typically including annotation, intersection, and merging of data from ...
William W. Greenwald, He Li, Erin N. Smith, Paola Benaglio, Naoki Nariai, Kelly A. Frazer   +5 more
doaj   +1 more source

Deep anterior lamellar keratoplasty in the management of keratoconus

Indian Journal of Ophthalmology, 2013
Advanced cases of keratoconus often require surgical intervention to restore corneal anatomy and improve eyesight. Penetrating keratoplasty (PK) although commonly performed has potential risk of immunological rejection and is now no longer automatically ...
Rajesh Fogla
doaj   +1 more source

A two‐tier bioinformatic pipeline to develop probes for target capture of nuclear loci with applications in Melastomataceae

Applications in Plant Sciences, 2020
Premise Putatively single‐copy nuclear (SCN) loci, which are identified using genomic resources of closely related species, are ideal for phylogenomic inference.
Johanna R. Jantzen, Prabha Amarasinghe, Ryan A. Folk, Marcelo Reginato, Fabian A. Michelangeli, Douglas E. Soltis, Nico Cellinese, Pamela S. Soltis   +7 more
doaj   +1 more source

Review of current indications for combined very high fluence collagen cross-linking and laser in situ keratomileusis surgery

Indian Journal of Ophthalmology, 2013
In this brief review we will discuss the reasoning and evolution of our current use of combined very high-fluence collagen crosslinking and laser in situ keratomileusis.
Anastasios John Kanellopoulos, Gregory J Pamel   +1 more
doaj   +1 more source

Mapping of promoter usage QTL using RNA-seq data reveals their contributions to complex traits.

PLoS Computational Biology, 2022
Genomic variations are associated with gene expression levels, which are called expression quantitative trait loci (eQTL). Most eQTL may affect the total gene expression levels by regulating transcriptional activities of a specific promoter. However, the
Naoto Kubota, Mikita Suyama
doaj   +1 more source

Not All That Glitters Is Gold: The Paradox of CO-dependent Hydrogenogenesis in Parageobacillus thermoglucosidasius

Frontiers in Microbiology, 2021
The thermophilic bacterium Parageobacillus thermoglucosidasius has recently gained interest due to its ability to catalyze the water gas shift reaction, where the oxidation of carbon monoxide (CO) is linked to the evolution of hydrogen (H2) gas.
Habibu Aliyu, Pieter de Maayer, Anke Neumann   +2 more
doaj   +1 more source