Results 41 to 50 of about 1,321,379 (303)
Multiplexed single-cell profiling of chromatin states at genomic loci by expansion microscopy
bioRxiv, 2020 Proper regulation of genome architecture and activity is essential for the development and function of multicellular organisms. Histone modifications, acting in combination, specify these activity states at individual genomic loci.
Marcus A. Woodworth +6 more
semanticscholar +1 more source
Frontiers in Plant Science, 2023 Soybean (Glycine max) production is greatly affected by persistent and/or intermittent droughts in rainfed soybean-growing regions worldwide. Symbiotic N2 fixation (SNF) in soybean can also be significantly hampered even under moderate drought stress ...
Muhammad Arifuzzaman +5 more
doaj +1 more source
Genome-wide scan for loci of Asperger syndrome [PDF]
Molecular Psychiatry, 2004 Asperger syndrome (AS), characterised by inadequate social interaction, lack of empathy and a dependence of routines and rituals, is classified as belonging to the autism spectrum disorders (DSM-IV and ICD-10). Although the prevalence of AS has been estimated to range from 0.3 up to 48.4 per 10 000, the phenotype still remains relatively unrecognised ...
T, Ylisaukko-oja +7 more
openaire +2 more sources
Genome Research, 2020 The higher-order structural organization and dynamics of the chromosomes play a central role in gene regulation. To explore this structure–function relationship, it is necessary to directly visualize genomic elements in living cells. Genome imaging based
Narendra Chaudhary +6 more
semanticscholar +1 more source
A Genome-Wide Screen for Hyposmia Susceptibility Loci [PDF]
Chemical Senses, 2008 Olfactory dysfunction is an important public health problem in the United States, with approximately 14 million elderly Americans having chronic olfactory impairment. We performed a genome-wide linkage scan for loci influencing susceptibility to hyposmia in the Hutterites, a founder population of European ancestry.
Jayant M, Pinto +4 more
openaire +2 more sources
Toric implantable collamer lens for keratoconus
Indian Journal of Ophthalmology, 2013 Keratoconus is a progressive non-inflammatory thinning of the cornea that induces myopia and irregular astigmatism and decreases the quality of vision due to monocular diplopia, halos, or ghost images.
Mathew Kurian Kummelil +6 more
doaj +1 more source
Highly Multiplexed Single-Cell In Situ RNA and DNA Analysis by Consecutive Hybridization
Molecules, 2020 The ability to comprehensively profile nucleic acids in individual cells in their natural spatial contexts is essential to advance our understanding of biology and medicine. Here, we report a novel method for spatial transcriptomics and genomics analysis.
Lu Xiao, Renjie Liao, Jia Guo
doaj +1 more source
PLoS ONE, 2020 The soybean is agro-economically the most important among all cultivated legume crops, and its seed color is considered one of the most attractive factors in the selection-by-breeders.
Jin-Hyun Kim +7 more
semanticscholar +1 more source
Purification of Proteins Associated with Specific Genomic Loci [PDF]
Cell, 2009 Eukaryotic DNA is bound and interpreted by numerous protein complexes in the context of chromatin. A description of the full set of proteins that regulate specific loci is critical to understanding regulation. Here, we describe a protocol called proteomics of isolated chromatin segments (PICh) that addresses this issue.
Déjardin, Jérôme, Kingston, Robert E.
openaire +2 more sources
Proteomic and gene expression patterns of keratoconus
Indian Journal of Ophthalmology, 2013 Keratoconus is a progressive corneal thinning disease associated with significant tissue remodeling activities and activation of a variety of signaling networks.
Arkasubhra Ghosh +4 more
doaj +1 more source