Results 61 to 70 of about 63,560 (282)

Antero-posterior ectoderm patterning by canonical Wnt signaling during ascidian development. [PDF]

PLoS Genetics, 2019
Wnt/β-catenin signaling is an ancient pathway in metazoans and controls various developmental processes, in particular the establishment and patterning of the embryonic primary axis. In vertebrates, a graded Wnt activity from posterior to anterior endows
Stacy Feinberg, Agnès Roure, Julie Piron, Sébastien Darras   +3 more
doaj   +1 more source

Single‐Cell Mitochondrial Lineage Tracing Decodes Fate Decision and Spatial Clonal Architecture in Human Hematopoietic Organoids

Advanced Science, EarlyView.
This study repurposes mitochondrial DNA mutations as endogenous barcodes for lineage tracing in human pluripotent stem cell‐derived organoids. Integrated with transcriptomic and spatial data, it reveals NOTCH‐mediated stromal‐progenitor crosstalk orchestrates clonal dynamics and spatial zonation during early hematopoietic development, offering a non ...
Yan Xue, Junhao Su, Yiming Chao, Lu Liu, Xinyi Lin, Yang Xiang, Mun Kay Ho, Zezhuo Su, Junyi Chen, Zhuojuan Luo, Chengqi Lin, Ruibang Luo, Theo Aurich, Jianfeng Wu, Kelvin Sin Chi Cheung, Yuanhua Huang, Joshua W. K. Ho, Ryohichi Sugimura   +17 more
wiley   +1 more source

Establishing neuronal identity in vertebrate neurogenic placodes [PDF]

, 2000
The trigeminal and epibranchial placodes of vertebrate embryos form different types of sensory neurons. The trigeminal placodes form cutaneous sensory neurons that innervate the face and jaws, while the epibranchial placodes (geniculate, petrosal and ...
Baker, Clare V. H., Bronner-Fraser, Marianne   +1 more
core  

Study of clinical profile of dermatophytosis in a tertiary care center as per ECTODERM guidelines

Asian Journal of Medical Sciences, 2021
Background: Dermatophytic infections are one of the most common skin infections encountered by dermatologists. A recent increase in incidence has been seen over the last few years with substantial change in the clinical profile of patients.
Shitij Goel , Shivam Dr , Azra Ferheen Chaudhary   +2 more
doaj   +1 more source

Ectodermal Dysplasias Revisited [PDF]

Acta geneticae medicae et gemellologiae, 1977
This paper presents a historical view of the development of the concept of ectodermal dysplasia, analyses five current “definitions” of the group, and classifies 52-57 ectodermal dysplasias into subgroups on the basis of criteria developed by the Author.
openaire   +2 more sources

Body Cavity Development Is Guided by Morphogen Transfer between Germ Layers

Cell Reports, 2018
Summary: The body cavity is a space where internal organs develop and are placed. Despite the importance of this internal space, how the body cavity forms specifically within the mesoderm remains largely unknown.
Jan Schlueter, Takashi Mikawa
doaj   +1 more source

Noonan Syndrome Spectrum Disorders Predispose to Systemic Lupus Erythematosus: Case Report and Critical Review of the Literature

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT RASopathies are clinically overlapping neurodevelopmental syndromes resulting from germline mutations in genes involved in the rat sarcoma/mitogen‐activated protein kinases (RAS/MAPK) pathway. Historically, RASopathies have been described by clinical phenotypes, such as Noonan syndrome and Neurofibromatosis type I.
Anastasia‐Vasiliki Madenidou, Gillian I. Rice, James O'Sullivan, Ben Parker, Ian N. Bruce, Emma Burkitt‐Wright, Tracy A. Briggs   +6 more
wiley   +1 more source

LvNotch signaling plays a dual role in regulating the position of the ectoderm-endoderm boundary in the sea urchin embryo [PDF]

, 2001
The molecular mechanisms guiding the positioning of the ectoderm-endoderm boundary along the animal-vegetal axis of the sea urchin embryo remain largely unknown.
McClay, David R., Sherwood, David R.
core  

BMP-dependent patterning of ectoderm tissue material properties modulates lateral mesendoderm cell migration during early zebrafish gastrulation

Cell Reports
Summary: Cell migration is a fundamental process during embryonic development. Most studies in vivo have focused on the migration of cells using the extracellular matrix (ECM) as their substrate for migration.
Stefania Tavano, David B. Brückner, Saren Tasciyan, Xin Tong, Roland Kardos, Alexandra Schauer, Robert Hauschild, Carl-Philipp Heisenberg   +7 more
doaj   +1 more source

Ectoderm-derived frontal bone mesenchymal stem cells promote traumatic brain injury recovery by alleviating neuroinflammation and glutamate excitotoxicity partially via FGF1

Stem Cell Research & Therapy, 2022
Background Traumatic brain injury (TBI) leads to cell and tissue impairment, as well as functional deficits. Stem cells promote structural and functional recovery and thus are considered as a promising therapy for various nerve injuries.
Qiaozhen Qin, Ting Wang, Zhenhua Xu, Shuirong Liu, Heyang Zhang, Zhangzhen Du, Jianing Wang, Yadi Wang, Zhenning Wang, Shanshan Yuan, Jiamei Wu, Wenyan He, Changzhen Wang, Xinlong Yan, Yan Wang, Xiaoxia Jiang   +15 more
doaj   +1 more source