Dental crown morphological variation and heterodonty in carcharhiniform sharks
Abstract Elasmobranch teeth are highly mineralized structures that constitute the majority of the fossil record for this group. Despite their taxonomic and evolutionary significance, detailed descriptions of dental morphology remain scarce. The order Carcharhiniformes, the most diverse among sharks, comprises 304 valid species that display remarkable ...
Flávia Zanini, Karla D. A. Soares
wiley +1 more source
Conserving genetic material and even increasing genetic diversity is critical. To conduct the conservation of wild boar germplasm resources, we have successfully obtained healthy cloned wild boars for the first time using interspecies somatic cell nuclear transfer and established transgene‐free iPSCs that can be used to conduct iterative rounds of gene
Chen Gao +11 more
wiley +1 more source
Evaluation of commonly used ectoderm markers in iPSC trilineage differentiation. [PDF]
Patient-derived induced pluripotent stem cells (iPSCs) have become a promising resource for exploring genetics of complex diseases, discovering new drugs, and advancing regenerative medicine.
Iacovino, Michelina +11 more
core
Cellular aspect ratio and cell division mechanics underlie the patterning of cell progeny in diverse mammalian epithelia. [PDF]
Cell division is essential to expand, shape, and replenish epithelia. In the adult small intestine, cells from a common progenitor intermix with other lineages, whereas cell progeny in many other epithelia form contiguous patches.
Castillo-Azofeifa, David +7 more
core +1 more source
Differential genetic mutations of ectoderm, mesoderm, and endoderm-derived tumors in TCGA database
Background In terms of biological behavior, gene regulation, or signaling pathways, there is a certain similarity between tumorigenesis and embryonic development of humans. Three germ layer structure exhibits the distinct ability to form specific tissues
Xingjie Gao +10 more
doaj +1 more source
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu +9 more
wiley +1 more source
Gene regulatory networks that control the specification of neural-crest cells in the lamprey [PDF]
The lamprey is the only basal vertebrate in which large-scale gene perturbation analyses are feasible at present. Studies on this unique animal model promise to contribute both to the understanding of the basic neural-crest gene regulatory network ...
Bronner-Fraser, Marianne +1 more
core +1 more source
Three-Dimensional Trilineage Differentiation Conditions for Human Induced Pluripotent Stem Cells
Human induced pluripotent stem cells (hiPSCs) hold great potential for regenerative medicine. However, optimizing their differentiation into specific lineages within three-dimensional (3D) scaffold-based culture systems that mimic in vivo environments ...
Md Sharifur Rahman +7 more
doaj +1 more source
A comprehensive embryonic staging series of the turtle Trachemys scripta
Abstract Background Turtles hold a unique place in vertebrate evolutionary history, making them critical assets in embryology research. Yet, they remain understudied as potential model organisms in the field. Here, to support experimental manipulations with turtle embryos, we have created a complete normal table of development for comprehensive ...
Christina M. Noravian +6 more
wiley +1 more source
Origins of the avian neural crest: the role of neural plate-epidermal interactions [PDF]
We have investigated the lineage and tissue interactions that result in avian neural crest cell formation from the ectoderm. Presumptive neural plate was grafted adjacent to non-neural ectoderm in whole embryo culture to examine the role of tissue ...
Bronner-Fraser, Marianne +1 more
core

