Results 21 to 30 of about 116,653 (132)

Anticalcification effects of DS-1211 in pseudoxanthoma elasticum mouse models and the role of tissue-nonspecific alkaline phosphatase in ABCC6-deficient ectopic calcification

Scientific Reports, 2022
Pseudoxanthoma elasticum (PXE) is a multisystem, genetic, ectopic mineralization disorder with no effective treatment. Inhibition of tissue-nonspecific alkaline phosphatase (TNAP) may prevent ectopic soft tissue calcification by increasing endogenous ...
Kaori Soma, Kengo Watanabe, Masanori Izumi   +2 more
doaj   +1 more source

Innovative Flow Cytometry Allows Accurate Identification of Rare Circulating Cells Involved in Endothelial Dysfunction. [PDF]

PLoS ONE, 2016
INTRODUCTION:Although rare, circulating endothelial and progenitor cells could be considered as markers of endothelial damage and repair potential, possibly predicting the severity of cardiovascular manifestations.
Federica Boraldi, Angelica Bartolomeo, Sara De Biasi, Stefania Orlando, Sonia Costa, Andrea Cossarizza, Daniela Quaglino   +6 more
doaj   +1 more source

ENPP1 variants in patients with GACI and PXE expand the clinical and genetic heterogeneity of heritable disorders of ectopic calcification.

PLoS Genetics, 2022
Pseudoxanthoma elasticum (PXE) and generalized arterial calcification of infancy (GACI) are clinically distinct genetic entities of ectopic calcification associated with differentially reduced circulating levels of inorganic pyrophosphate (PPi), a potent
Douglas Ralph, Yvonne Nitschke, Michael A Levine, Matthew Caffet, Tamara Wurst, Amir Hossein Saeidian, Leila Youssefian, Hassan Vahidnezhad, Sharon F Terry, Frank Rutsch, Jouni Uitto, Qiaoli Li   +11 more
doaj   +1 more source

Genomic Diagnoses for Ectopic Intracerebral Calcifications

Neurology Genetics, 2023
Ectopic intracerebral calcifications (EICs) in the basal ganglia, thalamus, cerebellum, or white matter are seen in a variety of disease states or may be found incidentally on brain imaging. The clinical significance and proportion of cases attributable to an underlying genetic cause is unknown.This retrospective cohort study details the clinical ...
Xiao, Changrui, Cassini, Thomas, Benavides, Daniel, Ebrahim, Anusha, Adams, David, Toro, Camilo   +5 more
openaire   +4 more sources

Ectopic Calcification in caALK2 mice [PDF]

, 2020
Background: Ectopic calcification can arises from several complicated diseases such as Fibrodysplasia Ossificans Progressiva (FOP). FOP is a rare congenital disorder of progressive and widespread ectopic classification which can extends to skeletal ...
Tasya Dentria Chiefianggi
core   +1 more source

Early diagnosis of aortic calcification through dental X-ray examination for dental pulp stones

Scientific Reports, 2023
Vascular calcification, an ectopic calcification exacerbated by aging and renal dysfunction, is closely associated with cardiovascular disease. However, early detection indicators are limited.
Misao Ishikawa, Hiroyuki Kanzaki, Ryo Kodera, Takehiro Sekimizu, Satoshi Wada, Syunnosuke Tohyama, Tomomi Ida, Miho Shimoyama, Shugo Manase, Hiroshi Tomonari, Noriyuki Kuroda   +10 more
doaj   +1 more source

Coffee consumption and coronary calcification: The Rotterdam coronary calcification study [PDF]

, 2008
BACKGROUND - The role of coffee in the cardiovascular system is not yet clear. We examined the relation of coffee intake with coronary calcification in a population-based cohort.
Hofman, A. (Albert), Witteman, JCM, Matthijs Oudkerk, Vliegenthart, R. (Rozemarijn), Hofman, Albert, Albert Hofman, Hofman, Bert, Oudkerk, M. (Matthijs), Geertruida J. van Woudenbergh, van Rooij, FJA; id_orcid, Geleijnse, J.M., Vliegenthart, R (Rozemarijn), Geleijnse, J.M. (Marianne), Rooij, F.J.A. (Frank) van, Vliegenthart, R., Rozemarijn Vliegenthart, Jacqueline C.M. Witteman, Rooij, F.J.A., van, Geleijnse, Johanna M., Witteman, J.C.M. (Jacqueline), van Rooij, Frank J. A., Geleijnse, JM (Marianne), Witteman, J.C.M., Oudkerk, Matthijs; id_orcid, Johanna M. Geleijnse, Hofman, A., van Woudenbergh, Geertruida J., van Woudenbergh, G.J., Woudenbergh, G.J., van, Woudenbergh, G.J. (Geertruida) van, van Rooij, F.J.A., van Woudenbergh, GJ, Oudkerk, Matthijs, Witteman, Jacqueline C. M., Vliegenthart, Rozemarijn, Oudkerk, M., Frank J.A. van Rooij, Oudkerk, M   +37 more
core   +1 more source

Multiple jaw cysts and ectopic calcification [PDF]

BMJ Case Reports, 2017
A 41-year-old woman presented with pus discharge from the gingival pocket and a 10-year history of intermittent buccal swelling on the left side. Physical examination revealed increased height, macrocephaly, hypertelorism, wide nasal bridge and sloping shoulders. Orthopantomography showed multiple jaw cysts (figure 1).
Satoshi, Hino, Hiroshi, Tanaka, Hiroyuki, Hamakawa   +2 more
openaire   +2 more sources

Vascular Calcification: New Insights Into BMP Type I Receptor A

Frontiers in Pharmacology, 2022
Vascular calcification (VC) is a complex ectopic calcification process and an important indicator of increased risk for diabetes, atherosclerosis, chronic kidney disease, and other diseases.
Zhixing Niu, Guanyue Su, Tiantian Li, Hongchi Yu, Yang Shen, Demao Zhang, Demao Zhang, Xiaoheng Liu   +7 more
doaj   +1 more source

An unusual ectopic calcification in the left atrium [PDF]

European Journal of Cardio-Thoracic Surgery, 2011
Please cite this article in press as: Akita M, et al. An unusual ectopic doi:10.1016/j.ejcts.2011.05.013 * Corresponding author. Address: Department of Cardiovascular Surgery, Kasukabe Chuo General Hospital, 5-9-4 Midori cho, Kasukabe, Saitama 3440063, Japan. Tel.: +81 48 736 1221; fax: +81 48 735 1559. E-mail address: markun@estate.ocn.ne.jp (M. Akita)
Masafumi, Akita, Kyoko, Urashima, Shin, Hagiwara, Junzo, Inamura   +3 more
openaire   +2 more sources