Results 21 to 30 of about 139,269 (266)
Ectopic Calcification as Discernible Manifestation in Neonates with Pseudohypoparathyroidism Type 1a [PDF]
International Journal of Endocrinology, 2009 The diagnosis of pseudohypoparathyroidism type 1a (PHP1a) is challenging, because both the osteodystrophy, such as brachydactyly and round face, and the symptomatic hypocalcemia usually develop beyond infancy.
Masanori Adachi +5 more
doaj +2 more sources
Inhibition of the DNA Damage Response Attenuates Ectopic Calcification in Pseudoxanthoma Elasticum. [PDF]
J Invest Dermatol, 2022 Pseudoxanthoma elasticum (PXE) is a heritable ectopic calcification disorder with multiorgan clinical manifestations. The gene at default, ABCC6, encodes an efflux transporter, ABCC6, which is a critical player regulating the homeostasis of inorganic ...
Huang J +5 more
europepmc +2 more sources
Minocycline Counteracts Ectopic Calcification in a Murine Model of Pseudoxanthoma Elasticum: A Proof-of-Concept Study [PDF]
International Journal of Molecular Sciences, 2022 Lukas Nollet +2 more
exaly +2 more sources
25-hydroxyvitamin D-1α-hydroxylase (CYP27B1) induces ectopic calcification. [PDF]
J Clin Biochem Nutr, 2022 Vascular calcification is an important pathogenesis related to cardiovascular disease and high mortality rate in chronic kidney disease (CKD) patients. It has been well-known that hyperphosphatemia induces osteochondrogenic transition of vascular smooth
Yimamu Y +10 more
europepmc +2 more sources
Ectopic Calcification in Congenital Heart Surgery: A Material-Centric Review [PDF]
Pediatric CardiologyTatsuya Watanabe, John Kelly
exaly +2 more sources
Advances in Pseudoxanthoma Elasticum
罕见病研究, 2023 Pseudoxanthoma elasticum(PXE) is a rare, genetic, metabolic disease characterized by ectopic calcification of connective tissue that primarily affects the skin, retina and cardiovascular system, which characteristic histopathology is calcification and ...
WANG Huifen, ZHAI Zhifang
doaj +1 more source
The Case | Ectopic calcifications in a child [PDF]
Kidney International, 2015 A 9-year-old boy, born of third-degree consanguinity, presented with a hard left scapular swelling that had been persistent for 6 months. There was no history of fever, trauma, or weight loss. There was no pain, redness, or discharge. This mass was excised but recurred over the next 6 months (left panel of Figure 1). A similar swelling had been excised
Keskar, Vaibhav S. +6 more
openaire +2 more sources
Bone Reports, 2021 Equilibrative nucleoside transporter 1 (ENT1) transfers nucleosides, such as adenosine, across plasma membranes. We reported previously that mice lacking ENT1 (ENT1−/−) exhibit progressive ectopic calcification of spinal tissues—a phenotype resembling ...
Dale E. Fournier +5 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2022 Tyrosine kinase inhibitors (TKIs) are widely used in cancer treatment due to their effectiveness in cancer cell killing. However, an off-target of this agent limits its success. Cardiotoxicity-associated TKIs have been widely reported. Tyrosine kinase is
Ainun Nizar Masbuchin +5 more
doaj +1 more source
Cell death in ectopic calcification of the kidney. [PDF]
Cell Death Dis, 2019 Priante G +7 more
europepmc +4 more sources