Multiple jaw cysts and ectopic calcification. [PDF]
BMJ Case Rep, 2017 A 41-year-old woman presented with pus discharge from the gingival pocket and a 10-year history of intermittent buccal swelling on the left side. Physical examination revealed increased height, macrocephaly, hypertelorism, wide nasal bridge and sloping shoulders. Orthopantomography showed multiple jaw cysts (figure 1).
Hino S, Tanaka H, Hamakawa H.
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The role of sodium phosphate cotransporters in ectopic calcification
Endokrynologia Polska, 2019 Phosphate plays a critical role in many vital cellular processes. Deviations from normal serum phosphate levels, including alterations in the extracellular phosphate/pyrophosphate ratio, can cause severe consequences, such as ectopic calcification. Cellular phosphate levels are tightly controlled by sodium phosphate cotransporters, underscoring their ...
Sergio, Gonzalo, Ricardo, Villa-Bellosta
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Role of carbonic anhydrase II in ectopic calcification [PDF]
Cardiovascular Pathology, 2009 Osteopontin (OPN) is a potent inhibitor of ectopic calcification. Previous studies suggested that, in addition to blocking apatite crystal growth, OPN promoted regression of ectopic calcification by inducing the expression of acid-generating carbonic anhydrase II (CAR2) in monocyte-derived cells.To test this hypothesis, OPN and CAR2 expression and ...
Rupak M Rajachar
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25-hydroxyvitamin D-1α-hydroxylase (CYP27B1) induces ectopic calcification. [PDF]
J Clin Biochem Nutr, 2022 Vascular calcification is an important pathogenesis related to cardiovascular disease and high mortality rate in chronic kidney disease (CKD) patients. It has been well-known that hyperphosphatemia induces osteochondrogenic transition of vascular smooth
Yimamu Y +10 more
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Converging Mechanisms of Vascular and Cartilaginous Calcification
BiologyPhysiological calcification occurs in bones and epiphyseal cartilage as they grow, whereas ectopic calcification occurs in blood vessels, cartilage, and soft tissues.
Simona R. Gheorghe +7 more
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Weighing the Evidence for the Roles of Plasma Versus Local Pyrophosphate in Ectopic Calcification Disorders [PDF]
Journal of Bone and Mineral Research, 2023 Douglas Ralph +2 more
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KIF26B Silencing Prevents Osseous Transdifferentiation of Progenitor/Stem Cells and Attenuates Ectopic Calcification in a Murine Model [PDF]
Journal of Bone and Mineral Research, 2022 Xin Duan, Lei Cai, Matthew J Silva
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Ectopic Calcification as Discernible Manifestation in Neonates with Pseudohypoparathyroidism Type 1a [PDF]
International Journal of Endocrinology, 2009 The diagnosis of pseudohypoparathyroidism type 1a (PHP1a) is challenging, because both the osteodystrophy, such as brachydactyly and round face, and the symptomatic hypocalcemia usually develop beyond infancy.
Masanori Adachi +5 more
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Inhibition of the DNA Damage Response Attenuates Ectopic Calcification in Pseudoxanthoma Elasticum. [PDF]
J Invest Dermatol, 2022 Pseudoxanthoma elasticum (PXE) is a heritable ectopic calcification disorder with multiorgan clinical manifestations. The gene at default, ABCC6, encodes an efflux transporter, ABCC6, which is a critical player regulating the homeostasis of inorganic ...
Huang J +5 more
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Mechanisms of ectopic calcification: implications for diabetic vasculopathy. [PDF]
Cardiovasc Diagn Ther, 2015 Vascular calcification (VC) is the deposition of calcium/phosphate in the vasculature, which portends a worse clinical outcome and predicts major adverse cardiovascular events. VC is an active process initiated and regulated via a variety of molecular signalling pathways. There are mainly two types of calcifications: the media VC and the intima VC. All
Avogaro A, Fadini GP.
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