Results 101 to 110 of about 183,658 (172)

Innate and Adaptive Immunity in Calcific Aortic Valve Disease

Journal of Immunology Research, 2015
Calcific aortic valve disease (CAVD) is the most common heart valve disorder. CAVD is a chronic process characterized by a pathologic mineralization of valve leaflets.
Patrick Mathieu, Rihab Bouchareb, Marie-Chloé Boulanger   +2 more
doaj   +1 more source

Hypophosphataemia in adults: approach to diagnosis and management

Internal Medicine Journal, EarlyView.
Abstract Hypophosphataemia is a common electrolyte disorder which can have clinically significant consequences for bone, muscle, neurological and haematological function. Its causes range from transient transcellular shifts in hospitalised patients to chronic renal phosphate‐wasting disorders mediated by fibroblast growth factor 23 (FGF23).
Kajanan Parameshwaran, Mawson Wang, Kirtan Ganda   +2 more
wiley   +1 more source

Animal models with pathological mineralization phenotypes

, 2011
Extracellular matrix mineralization is important for mechanical stability of the skeleton and for calcium and phosphate storage. Professional mineral-disposing cell types are hypertrophic chondrocytes, odontoblasts, ameloblasts and osteoblasts.
Kornak, U.
core   +2 more sources

Ectopic mineralization of cartilage and collagen-rich tendons and ligaments in Enpp1asj-2J mice. [PDF]

, 2016
Generalized arterial calcification of infancy (GACI), an autosomal recessive disorder caused by mutations in the ENPP1 gene, manifests with extensive mineralization of the cardiovascular system. A spontaneous asj-2J mutant mouse has been characterized as
Zhang, Jieyu, Rowe, David W, Uitto, Jouni, Dyment, Nathaniel A, Sundberg, John P, Li, Qiaoli, Siu, Sarah Y   +6 more
core   +1 more source

Eccentric Occlusal Loads Remodel the Dentoalveolar and Temporomandibular Biomechanical Unit in Rats

Journal of Oral Rehabilitation, EarlyView.
Eccentric occlusal loads remodel the dentoalveolar and temporomandibular joints in the masticatory biomechanical unit in rats. (A) Bite block as an occlusal rise (OR) on the rat maxillary first molar (green region) is shown. (B) 18F‐NaF Positron emission tomography localised regions of higher metabolic activity (higher uptake in the left condyle ...
Haochen Ci, Umama Ali, Zhiyuan Yang, Ayush Bakhandi, Nhu Huynh, Christine Nguyen, Brandon Lee, Youngho Seo, Robert Flavell, Alireza Hatamifar, Rishi J. Gupta, Rebeka Silva, Yongmei Wang, Bo Wang, Sunita P. Ho   +14 more
wiley   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Hexasodium Fytate (SNF472 or CSL525) Inhibits Ectopic Calcification in Various Pseudoxanthoma Elasticum and Calcinosis Cutis Animal Models

Pharmaceuticals
Background/Objectives: Ectopic calcification is a pathological condition characterized by the mineralization of soft tissues due to the deposition of calcium phosphate crystals.
Miguel D. Ferrer, Maria del Mar Pérez-Ferrer, Marc Blasco, Ida Joely Jacobs, Qiaoli Li, Olivier M. Vanakker, Lisa Dangreau, Andrea López, Gianluca Malagraba, Firas Bassissi, Joan Perelló, Carolina Salcedo   +11 more
doaj   +1 more source

Bone Grafts: Everything You Need to Know

Journal of Periodontal Research, EarlyView.
This review classifies bone grafts (autograft, allograft, xenograft, synthetic) by source and osteogenic/inductive/conductive potential, linking material properties and mechanisms to clinical indications in periodontal and dental regeneration. Key challenges—limited osteoinduction, poor vascularisation, unbalanced resorption, handling difficulties, and
Håvard Jostein Haugen, Javier Sanz, Giuseppe Perale, Augustine Mark Saiz, Mario Romandini, Maryam Rahmati   +5 more
wiley   +1 more source

Plasma PPi Deficiency Is the Major, but Not the Exclusive, Cause of Ectopic Mineralization in an Abcc6(-/-) Mouse Model of PXE.

, 2017
Pseudoxanthoma elasticum (PXE), a prototype of heritable ectopic mineralization disorders, is caused in most cases by inactivating mutations in the ABCC6 gene.
Zhao, Jingyi, Qiaoli Li, John P. Sundberg, Jouni Uitto, Uitto, Jouni, Kingman, Joshua, Sundberg, John P, Li, Qiaoli, Jingyi Zhao, Joshua Kingman   +9 more
core   +1 more source

Periodontitis and Inflammatory Bowel Diseases: Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This review aims to provide a conceptual framework for understanding the mechanistic interplay between periodontitis and IBD, with a particular emphasis on the microbial and immunological crosstalk linking the oral cavity and the gastrointestinal tract.
Ana Paula V. Colombo, Adriana M. de Oliveira, Nobuhiko Kamada, Sho Kitamoto   +3 more
wiley   +1 more source