Process of ectopic tooth formation in the maxillary sinus: follow-up observation of one case
Journal of International Medical Research, 2019 Objective This study was performed to investigate the process of ectopic tooth formation. Methods A patient with an ectopic tooth was followed for 6 years.
Jinfeng Liu +4 more
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Etidronate prevents, but does not reverse, ectopic mineralization in a mouse model of pseudoxanthoma elasticum ( [PDF]
, 2018 Pseudoxanthoma elasticum (PXE) and generalized arterial calcification of infancy (GACI) are heritable disorders manifesting with ectopic tissue mineralization.
Uitto, Jouni +4 more
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Histomorphometry of ectopic mineralization using undecalcified frozen bone sections
Histomorphometry of ectopic mineralization using undecalcified frozen bone sectionsTo investigate the correlation between mineral formation and enhanced expressions of some proteins using undecalcified frozen bone sections. Histological studies have revealed that some proteins, such as BMP2, BMPR1A, and Connexin 43, are expressed in and around sites of ectopic ossification.
フジハラ, リュウジ +2 more
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Biomolecules, 2021 Tissue-nonspecific alkaline phosphatase (TNAP) is a key enzyme responsible for skeletal tissue mineralization. It is involved in the dephosphorylation of various physiological substrates, and has vital physiological functions, including extra-skeletal ...
Saravanan Sekaran +2 more
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Rare Co-occurrence of Beta-Thalassemia and Pseudoxanthoma elasticum: Novel Biomolecular Findings
Frontiers in Medicine, 2020 A number of beta-thalassemia patients, independently from the type of beta-thalassemia (β0 or β+) and blood transfusion requirements, may develop, after puberty, dermal, cardiovascular, and ocular complications associated with an ectopic mineralization ...
Federica Boraldi +4 more
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Ectopic Mineralization of Hen Leg Tendon.
Japanese Journal of Oral Biology, 2001 生後1年以上のニワトリの足の腱には, 石灰化物の沈着がみられる。さらに, 電子顕微鏡観察によれば, すでに生後100日以上の個体においてその徴候が認められる。本研究では, ニワトリ足腱の異所性石灰化部位の無機成分と有機マトリックス成分をプラズマ重合膜法によりオスミウムコートし, その走査電子顕微鏡観察を行った。その結果, コラーゲンマトリックスと石灰化物のそれぞれに, 新規の構造物を見いだした。第1に, 有機成分を溶解した後には長径が1.86±0.38μm (平均±標準偏差), 短径が1.05±0.16μm (平均±標準偏差) の楕円形の石灰化顆粒がみられ, それらはさらに融合して多数の細長いロッド状の構造を形成していた。さらに透過電顕観察では ...
Ono, Toshio, Nemoto, Takayuki
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Pseudoxanthoma Elasticum as a Paradigm of Heritable Ectopic Mineralization Disorders [PDF]
The American Journal of Pathology, 2019 Ectopic mineralization is a global problem and leading cause of morbidity and mortality. The pathomechanisms of ectopic mineralization are poorly understood. Recent studies on heritable ectopic mineralization disorders with defined gene defects have been helpful in elucidation of the mechanisms of ectopic mineralization in general.
Qiaoli, Li +2 more
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SMOC2 inhibits calcification of osteoprogenitor and endothelial cells. [PDF]
PLoS ONE, 2018 Tissue calcification is an important physiological process required for the normal structure and function of bone. However, ectopic or excessive calcification contributes to diseases such as chondrocalcinosis, to calcium deposits in the skin or to ...
Tine Peeters +5 more
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Plasma Inorganic Pyrophosphate Deficiency Links Multiparity to Cardiovascular Disease Risk
Frontiers in Cell and Developmental Biology, 2020 Epidemiological studies indicate that elevated alkaline phosphatase activity is associated with increased cardiovascular disease risk. Other epidemiological data demonstrate that mothers giving multiple childbirths (multipara) are also at increased risk ...
Almudena Veiga-Lopez +14 more
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Functional Assessment of Missense Variants in the ABCC6 Gene Implicated in Pseudoxanthoma Elasticum, a Heritable Ectopic Mineralization Disorder. [PDF]
, 2022 Pseudoxanthoma elasticum, a heritable multisystem ectopic mineralization disorder, is caused by inactivating mutations in the ABCC6 gene. The encoded protein, ABCC6, a transmembrane transporter, has a specialized efflux function in hepatocytes by ...
Luo, Hongbin +6 more
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