Results 41 to 50 of about 178,374 (209)
Ectopic mineralization in fibroblast cultures.
Archivum histologicum japonicum, 1984 A human gingival fibroblast cell line was cultured in a DM-153 medium supplemented with 10% bovine serum. The cells in culture showed both intracellular and extracellular ectopic mineralization. Ultrastructurally, mineralization began within the round and irregularly shaped vesicles contained in large cytoplasmic vacuoles of fibroblasts.
KUMEGAWA, Masayoshi +2 more
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Osteopontin Inhibits Mineral Deposition and Promotes Regression of Ectopic Calcification [PDF]
The American Journal of Pathology, 2002 Ectopic calcification, the abnormal calcification of soft tissues, can have severe clinical consequences especially when localized to vital organs such as heart valves, arteries, and kidneys. Recent observations suggest that ectopic calcification, like bone biomineralization, is an actively regulated process.
Susan A, Steitz +6 more
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Process of ectopic tooth formation in the maxillary sinus: follow-up observation of one case
Journal of International Medical Research, 2019 Objective This study was performed to investigate the process of ectopic tooth formation. Methods A patient with an ectopic tooth was followed for 6 years.
Jinfeng Liu +4 more
doaj +1 more source
Biomolecules, 2021 Tissue-nonspecific alkaline phosphatase (TNAP) is a key enzyme responsible for skeletal tissue mineralization. It is involved in the dephosphorylation of various physiological substrates, and has vital physiological functions, including extra-skeletal ...
Saravanan Sekaran +2 more
doaj +1 more source
Plasma PPi Deficiency Is the Major, but Not the Exclusive, Cause of Ectopic Mineralization in an Abcc6-/- Mouse Model of PXE. [PDF]
J Invest Dermatol, 2017 Pseudoxanthoma elasticum (PXE), a prototype of heritable ectopic mineralization disorders, is caused in most cases by inactivating mutations in the ABCC6 gene.
Zhao J +4 more
europepmc +2 more sources
Histomorphometry of ectopic mineralization using undecalcified frozen bone sections
Histomorphometry of ectopic mineralization using undecalcified frozen bone sectionsTo investigate the correlation between mineral formation and enhanced expressions of some proteins using undecalcified frozen bone sections. Histological studies have revealed that some proteins, such as BMP2, BMPR1A, and Connexin 43, are expressed in and around sites of ectopic ossification.
フジハラ, リュウジ +2 more
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Ectopic mineralization of cartilage and collagen-rich tendons and ligaments in Enpp1asj-2J mice. [PDF]
Oncotarget, 2016 Generalized arterial calcification of infancy (GACI), an autosomal recessive disorder caused by mutations in the ENPP1 gene, manifests with extensive mineralization of the cardiovascular system. A spontaneous asj-2J mutant mouse has been characterized as
Zhang J +6 more
europepmc +3 more sources
Rare Co-occurrence of Beta-Thalassemia and Pseudoxanthoma elasticum: Novel Biomolecular Findings
Frontiers in Medicine, 2020 A number of beta-thalassemia patients, independently from the type of beta-thalassemia (β0 or β+) and blood transfusion requirements, may develop, after puberty, dermal, cardiovascular, and ocular complications associated with an ectopic mineralization ...
Federica Boraldi +4 more
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Ectopic Mineralization of Hen Leg Tendon.
Japanese Journal of Oral Biology, 2001 生後1年以上のニワトリの足の腱には, 石灰化物の沈着がみられる。さらに, 電子顕微鏡観察によれば, すでに生後100日以上の個体においてその徴候が認められる。本研究では, ニワトリ足腱の異所性石灰化部位の無機成分と有機マトリックス成分をプラズマ重合膜法によりオスミウムコートし, その走査電子顕微鏡観察を行った。その結果, コラーゲンマトリックスと石灰化物のそれぞれに, 新規の構造物を見いだした。第1に, 有機成分を溶解した後には長径が1.86±0.38μm (平均±標準偏差), 短径が1.05±0.16μm (平均±標準偏差) の楕円形の石灰化顆粒がみられ, それらはさらに融合して多数の細長いロッド状の構造を形成していた。さらに透過電顕観察では ...
Ono, Toshio, Nemoto, Takayuki
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SMOC2 inhibits calcification of osteoprogenitor and endothelial cells. [PDF]
PLoS ONE, 2018 Tissue calcification is an important physiological process required for the normal structure and function of bone. However, ectopic or excessive calcification contributes to diseases such as chondrocalcinosis, to calcium deposits in the skin or to ...
Tine Peeters +5 more
doaj +1 more source