Results 81 to 90 of about 2,289 (201)

95% effective dose of remimazolam in brachial plexus block assistedsedation and its efficacy and safety

Zhongguo linchuang yanjiu
Objective To investigate the 95% effective dose（ED95）of remimazolam for brachial plexus block（BPB）-assisted sedation and its effectiveness and safety, and to compare it with propofol. Methods Two-part clinical trials were conducted in patients undergoing
SI Zenghao，WANG Jinfeng，GAO Yuan，CHEN Bowen，WANG Weilian，ZHANG Kun
doaj   +1 more source

The little we know about the pharmacokinetics and pharmacodynamics of praziquantel (racemate and R-enantiomer) [PDF]

, 2017
Praziquantel has been the mainstay of schistosomiasis control since 1984 and widely distributed since 2006 through ‘preventive chemotherapy' programmes to school-aged children or at-risk populations.
Delgado-Romero, Petra, Keiser, Jennifer, Olliaro, Piero   +2 more
core  

Computer vision model for the detection of canine pododermatitis and neoplasia of the paw

Veterinary Dermatology, Volume 35, Issue 2, Page 138-147, April 2024.
Background – Artificial intelligence (AI) has been used successfully in human dermatology. AI utilises convolutional neural networks (CNN) to accomplish tasks such as image classification, object detection and segmentation, facilitating early diagnosis.
Andrew Smith, Patrick W. Carroll, Srikanth Aravamuthan, Emil Walleser, Haley Lin, Kelly Anklam, Dörte Döpfer, Neoklis Apostolopoulos   +7 more
wiley   +1 more source

Design considerations and analysis planning of a phase 2a proof of concept study in rheumatoid arthritis in the presence of possible non-monotonicity [PDF]

, 2017
BACKGROUND: It is important to quantify the dose response for a drug in phase 2a clinical trials so the optimal doses can then be selected for subsequent late phase trials.
AE Raftery, EH Choy, EJ Calabrese, F Behrens, Feng Liu, J Arrowsmith, J Fransen, J Heydari, K Almstrup, M Hay, MK Smith, N Thomas, P Brain, SC Owen, Stephen J. Walters, Steven A. Julious, W Stohl, Z Skrivanek   +17 more
core   +2 more sources

The 50% and 95% effective dose of remimazolam tosilate for anaesthesia induction in sleep disorders patients undergoing laparoscopic cholecystectomy: an up-and-down sequential allocation trial

BMC Anesthesiology
Purpose Previous reports argue that preoperative sleep conditions of patients can influence the dosage of general anaesthesia drugs. Therefore, we aimed to investigate the dose-effect relationship of preoperative sleep disorders on the induction of ...
Yue Xiao, Yanan Cao, Jie Pu, Chendong Guo, Yanzi Yi, Youming Deng, Yimin Hu   +6 more
doaj   +1 more source

Modélisation de l’apprenant et interactivité [PDF]

, 1999
Cet article présente les différents courants qui ont trait à la modélisation de l'apprenant dans le cadre de systèmes d'apprentissage informatisés. Parce qu'il concerne les caractéristiques de l'apprenant, le concept d'interactivité est directement relié
Giardina, Max, Laurier, Michel
core   +1 more source

ED95 of esketamine for reducing preoperative anxiety in children of different ages

Abstract Background: The incidence of preoperative anxiety in children is significantly higher than in adults. Esketamine, the dextrorotatory enantiomer of ketamine, has been shown to alleviate preoperative anxiety in children effectively. Previous studies have established the effective dose (ED
Xuming Zhu, Xiaoyong Wei, Qianyu Guo, Peipei Hao, Leting Ji   +4 more
openaire   +1 more source

Comparativo del proceso de Implementación de la energía solar Brasil VS Colombia [PDF]

, 2018
Visita Técnica InternacionalEn esta monografía se establece un comparativo en la implementación de energía solar en Brasil vs Colombia. Con la visita técnica Internacional Realizada en la Universidad de Sao Carlos en Brasil en la semana de la Ciencia y ...
Salguero-Parra, Jhon Orlando
core  

Region-specific depletion of synaptic mitochondria in the brains of patients with Alzheimer’s disease [PDF]

, 2018
Of all of the neuropathological changes observed in Alzheimer’s disease (AD), the loss of synapses correlates most strongly with cognitive decline. The precise mechanisms of synapse degeneration in AD remain unclear, although strong evidence indicates ...
Gillingwater, Thomas, Henstridge, Christopher, King, Declan, McCrory, C, McKenzie, Chris-Anne, Pickett, Eleanor, Rose, Jamie, Smith, Colin, Spires-Jones, Tara   +8 more
core   +3 more sources

Effect of Dexmedetomidine on the ED50 and ED95 of Sufentanil in Patient-Controlled Intravenous Analgesia After Cesarean Section: A Randomized, Controlled, Double-Blind Trial

Drug Design, Development and Therapy
Jiabei Li,1,2 Wuchang Fu,3 Na Wang,1 Sisi Zeng,1 Xuechao Li,1 Jixiang Wan,1 Fangjun Wang1 1Department of Anesthesiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, People’s Republic of China; 2Department of Anesthesiology, Meishan ...
Li J, Fu W, Wang N, Zeng S, Li X, Wan J, Wang F   +6 more
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