Results 81 to 90 of about 1,434 (182)

Median effective dose (ED50) of ciprofol combined with alfentanil for suppressing cervical dilation responses during hysteroscopy: a prospective Dixon up-and-down study

BMC Anesthesiology
Background Cervical dilation during hysteroscopy induces significant nociceptive stimulation that may provoke somatic response and compromise procedural conditions.
Conghui Zhang, Yunyan Zhu, Linghua Zeng, Junjie Zhu, Jing Chen, Ting Zhang, YuanMing Tao, Shihong Li, Maolin Zhong, Fuzhou Hua, Weidong Liang   +10 more
doaj   +1 more source

Intrathecal hydromorphone for postoperative pain management in gastrectomy: a dose-finding and randomized controlled study

Anesthesiology and Perioperative Science
Background Single-dose intrathecal hydromorphone or transversus abdominis plane (TAP) block has garnered growing interest as components of multimodal analgesia for gastrectomy.
Lin Ding, Yu Leng, Hongxin Liu, Xiaojuan Jiang, Jun Ma, Zhichao Gong, Chengyu Li, Cheng Zhou, Qian Li   +8 more
doaj   +1 more source

ED50 and ED95 of Remimazolam Tosilate Combined with Different Doses of Fentanyl in Elderly Patients for Painless Gastroscopy

Drug Design, Development and Therapy
The novel short-acting benzodiazepine drug, remimazolam tosilate, has been employed for sedation during endoscopic procedures. The optimal loading dosage of remimazolam tosilate in gastroscopy for elderly patients when co-administered with fentanyl remains unclear.
Guo,Yanxia, Yao,Zhihua, Feng,Yan, Wang,Dan, Wang,Yizheng, Lin,Jingyan   +5 more
openaire   +4 more sources

Minimum local anesthetic volumes for a selective saphenous nerve block: a dose-finding study

, 2017
BACKGROUND: Saphenous nerve block contributes to analgesia after knee and lower leg surgery. However, literature reports a wide range of volumes of local anesthetic being used for this block.
Hollmann, Markus W., Rigaud, Marcel, ten Hoope, Werner, Baumann, Holger M., Kerkhoffs, Gino M., Atchabahian, Arthur, Lirk, Philipp   +6 more
core   +1 more source

The case for integration andadaptation

, 2008
Proceedings ofAI-ED95-7thWorld Conference ...
Peter Brusilovsky, Jim Greer
core  

Pharmacokinetic/Pharmacodynamic Model of CW002, an Investigational Intermediate Neuromuscular Blocking Agent, in Healthy Volunteers

, 2018
BackgroundCW002 is an investigational nondepolarizing, neuromuscular blocking agent with a rapid onset and intermediate duration of action in animals. This is a single ascending dose, healthy subject study exploring tolerability, pharmacokinetics, and ...
Kim L. R. Brouwer, Virginia D. Schmith, Joel S. Owen, Paul M. Heerdt, Josh D. Kaullen, Cynthia A. Lien, John J. Savarese   +6 more
core   +1 more source

Analysis of the median effective dose and adverse effects of methylene blue combined with ropivacaine for fascia iliaca compartment block in postoperative analgesia in elderly patients undergoing hip arthroplasty

Shiyong laonian yixue
[Objective] To determine the median effective dose (ED50) and 95% effective dose (ED95) of methylene blue as an adjuvant to ropivacaine in elderly patients undergoing fascia iliaca compartment block for postoperative 24-hour effective analgesia without ...
ZHANG Yang, YANG Shun, LU Ziru, SHA Lili
doaj   +1 more source

Cisatracurium dose–response relationship in patients with chronic liver disease

, 2014
ObjectiveCisatracurium is approximately 3 times more potent than atracurium, devoid of histamine release and cardiovascular side effects and mainly eliminated by Hofmann degradation. Patients with liver disease exhibit abnormal response to most of muscle
El Sabea, Hossam H., Kamel, Inas, Ebied, Reeham S., Monaem, Amr Abd El, Abo-Sedira, Mounis A., Atallah, Maha A., Ali, Mohamed Z.   +6 more
core   +1 more source

Effective dose of intranasal remimazolam for preoperative sedation in preschool children: a dose-finding study using Dixon’s up-and-down method

Frontiers in Pharmacology
Background:Most preschool children are distressed during anesthesia induction. While current pharmacological methods are useful, there is a need for further optimization to an “ideal” standard.
Ming-Jie Ni, Yu-Ting Jin, Qian-Lin Wu, Ning Zhang, Jia-He Tian, Jun Li, Kai-Ming Yuan   +6 more
doaj   +1 more source

The Relaxant Effects of Propofol and Ketamine on Guinea-pig Tracheal Smooth Muscle

, 1997
BACKGROUND Propofol inhibits postoperative bronchospasm. Ketamine prevents bronchospasm in asthmatic patients. The present study was designed to evaluate the effects and mechanisms of propofol and ketamine on tracheal smooth muscles.
김원옥, 고신옥
core   +1 more source