Results 21 to 30 of about 1,370 (154)
Eukaryotic mRNA Decapping Activation
Frontiers in Genetics, 2022 The 5′-terminal cap is a fundamental determinant of eukaryotic gene expression which facilitates cap-dependent translation and protects mRNAs from exonucleolytic degradation.
Elva Vidya +3 more
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The Effect of Protein Tagging on Aggregation and Phase Separation. [PDF]
J Cell BiochemABSTRACT Protein tags are widely used for purification, solubilization, detection, and imaging, yet they can substantially alter protein self‐assembly. This interference is particularly significant for intrinsically disordered proteins and low‐complexity domains, whose aggregation and phase separation are mediated by weak multivalent interactions that ...
Saito H, Sugase K.
europepmc +2 more sources
Assembly and regulation of the mammalian mRNA processing body
PLoS ONE, 2023 Messenger RNA processing bodies (P-bodies) are cytoplasmic membrane-free organelles that contain proteins involved in mRNA silencing, storage and decay.
Donald B. Bloch +3 more
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An optimized multi-proxy, multi-site Antarctic ice and gas orbital chronology (AICC2012): 120–800 ka [PDF]
Climate of the Past, 2013 An accurate and coherent chronological framework is essential for the interpretation of climatic and environmental records obtained from deep polar ice cores.
L. Bazin +21 more
doaj +1 more source
Viruses, 2020 Broadly neutralizing monoclonal antibodies (bNAbs) against conserved domains in the influenza hemagglutinin are in clinical trials. Several next generation influenza vaccines designed to elicit such bNAbs are also in clinical development.
Surender Khurana +3 more
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Systematic identification of factors mediating accelerated mRNA degradation in response to changes in environmental nitrogen. [PDF]
PLoS Genetics, 2018 Cellular responses to changing environments frequently involve rapid reprogramming of the transcriptome. Regulated changes in mRNA degradation rates can accelerate reprogramming by clearing or stabilizing extant transcripts.
Darach Miller +2 more
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Insight into the interaction between the RNA helicase CGH-1 and EDC-3 and its implications
Scientific Reports, 2021 Previous studies indicated that the P-body components, CGH-1 and EDC-3 may play a crucial role in the regulation of lifespan in Caenorhabditis elegans. Homo sapiens DDX6 or Saccharomyces cerevisiae Dhh1p (CGH-1 in C.
Yong Zhang +4 more
doaj +1 more source
Molecular Cytogenetics, 2021 Chromosome 15q24 microdeletion is a rare genetic disorder characterized by development delay, facial dysmorphism, congenital malformations, and occasional autism spectrum disorder (ASD).
Yuanyuan Zhang +5 more
doaj +1 more source
Cell Reports, 2015 The DEAD-box protein DDX6 is a central component of translational repression mechanisms in maternal mRNA storage in oocytes and microRNA-mediated silencing in somatic cells.
Sevim Ozgur +5 more
doaj +1 more source
Analysis of the Physiological Activities of Scd6 through Its Interaction with Hmt1. [PDF]
PLoS ONE, 2016 Scd6, a yeast homologue of human RAP55, is a component of messenger ribonucleoproteins (mRNPs) that repress translation by binding to translation initiation factors, and also is a decapping activator along with the binding partners Edc3 and Dhh1. Herein,
Pham Thi Kim Lien +5 more
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