Results 21 to 30 of about 277,895 (300)

Bacillus anthracis edema factor substrate specificity: evidence for new modes of action [PDF]

, 2012
Since the isolation of Bacillus anthracis exotoxins in the 1960s, the detrimental activity of edema factor (EF) was considered as adenylyl cyclase activity only.
Stefan Dove, Göttle, Martin, Seifert, Roland, Martin Göttle, Roland Seifert, Dove, Stefan   +5 more
core   +1 more source

Risk Factors for Pulmonary Edema in Triplet Pregnancies [PDF]

Journal of Perinatology, 2003
Multiple gestations are known to be at increased risk for pulmonary edema. Our objective was to characterize this morbidity in a cohort of triplet pregnancies.Charts from triplet pregnancies managed by the Georgetown University Hospital Maternal-Fetal Medicine service were abstracted for demographic information and complications.
Sarah H, Poggi, Sybil, Barr, Rebecca, Cannum, Joseph V, Collea, Helain J, Landy, Martin, Kezsler, Alessandro, Ghidini   +6 more
openaire   +2 more sources

Anthrax Edema Factor: An Ion-Adaptive Mechanism of Catalysis with Increased Transition-State Conformational Flexibility

, 2016
Edema Factor (EF) is one of three major toxins of anthrax. EF is an adenylyl cyclase that disrupts cell signaling by accelerating the conversion of ATP into cyclic-AMP.
Gabriel E. Jara (1736659), Leandro Martínez (1279542)   +1 more
core   +3 more sources

Visual acuity and foveal thickness after vitrectomy for macular edema associated with branch retinal vein occlusion: a case series

BMC Ophthalmology, 2010
Background The mechanism by which vitrectomy improves macular edema in patients with branch retinal vein occlusion remains unclear, although intraocular levels of vascular endothelial growth factor have been suggested to influence the visual prognosis ...
Eguchi Shuichiro, Mimura Tatsuya, Funatsu Hideharu, Noma Hidetaka, Shimada Katsunori   +4 more
doaj   +1 more source

Mouse Monoclonal Antibodies to Anthrax Edema Factor Protect against Infection

, 2011
Bacillus anthracis is the causative agent of anthrax, and the tripartite anthrax toxin is an essential element of its pathogenesis. Edema factor (EF), a potent adenylyl cyclase, is one of the toxin components. In this work, anti-EF monoclonal
Rasem Fattah, Stephen H. Leppla, Suman R. Das, Zhaochun Chen, Clinton E. Leysath, Kuang-Hua Chen, Devorah Crown, Robert H. Purcell, Mahtab Moayeri   +8 more
core   +1 more source

One day wonder: Fast resolution of macular edema following intravitreal ranibizumab in retinal venous occlusions

Indian Journal of Ophthalmology, 2013
Macular edema is a significant cause of vision loss in patients with central retinal vein occlusions and branch retinal vein occlusions. Vascular endothelial growth factor (VEGF) appears to be a key factor in the pathogenesis of this disease.
Lalit Verma, Arindam Chakravarti, Avnindra Gupta, Smriti Prakash   +3 more
doaj   +1 more source

Molecular analysis of mammalian adenylyl cyclases and bacterial adenylyl cyclase toxins

, 2009
The cAMP signaling pathway is crucial for many physiological processes and many disease states like neurodegenerative diseases, mood disorders, pain, drug dependency or heart failure.
Göttle, Martin
core   +1 more source

Cerebral edema after ischemic stroke: Pathophysiology and underlying mechanisms

Frontiers in Neuroscience, 2022
Ischemic stroke is associated with increasing morbidity and has become the main cause of death and disability worldwide. Cerebral edema is a serious complication arising from ischemic stroke.
Yuhang Gu, Chen Zhou, Zhe Piao, Honghua Yuan, Huimin Jiang, Huimin Wei, Yifan Zhou, Guangxian Nan, Xunming Ji, Xunming Ji   +9 more
doaj   +1 more source

Changes in metamorphopsia after the treat-and-extend regimen of anti-VEGF therapy for macular edema associated with branch retinal vein occlusion.

PLoS ONE, 2020
This study aims to investigate the changes in metamorphopsia after administering the treat-and-extend regimen of anti-vascular endothelial growth factor therapy for branch retinal vein occlusion-associated macular edema.
Kenichiro Mori, Keijiro Ishikawa, Iori Wada, Yuki Kubo, Yoshiyuki Kobayashi, Takahito Nakama, Masatoshi Haruta, Masato Akiyama, Shintaro Nakao, Shigeo Yoshida, Koh-Hei Sonoda   +10 more
doaj   +1 more source

Idiopathic thrombocytopenic purpura and its fundus features in a patient with diabetes mellitus

Indian Journal of Ophthalmology, 2020
In this case report, we present a patient with thrombocytopenia secondary to idiopathic thrombocytopenic purpura (ITP), whose fundus appearance had features of diabetic retinopathy with macular edema.
R Rajesh, Mahesh P Shanmugam, Pradeep Sagar   +2 more
doaj   +1 more source