Results 31 to 40 of about 277,895 (300)
Bacillus anthracis overwhelms its victims by way of two toxins, namely edema toxin and lethal toxin. Lethal toxin is formed by the combination of protective antigen with lethal factor while edema toxin is formed by the combination of Protective Antigen ...
Bhatnagar, Rakesh +3 more
core +1 more source
Peripheral retinal leakage in POEMS syndrome
Background POEMS (polyneuropathy, organomegaly, endocrinopathy, myeloma protein, skin changes) syndrome is a rare blood disorder with multi-system involvement. The cause is unknown.
Andrew Rising Carey, Praveen Jeyaseelan
doaj +1 more source
Prevalence and Risk Factors of Pedal Edema in Chronic Leg Edema
This study aimed to determine the prevalence and underlying causes of pedal edema (PE) in legs affected by chronic edema.A total of 705 legs with chronic edema, defined as persistent leg edema lasting for > 3 months, were examined in 411 patients who visited our clinic between April 2009 and March 2024. Patients with known systemic edematous conditions
Kotaro, Suehiro +9 more
openaire +2 more sources
Abbreviations AC, adenylyl cyclase; ANT, anthraniloyl-; CaM, calmodulin; CyaA, Bordetella pertussis adenylyl cyclase toxin; ESI, electrospray ionization; FRET, fluorescence resonance energy transfer; HPLC, high pressure liquid chromatography; k, capacity
Jennifer Schmidt +16 more
core +2 more sources
Anti-vascular endothelial growth factor therapy for diabetic macular edema
Diabetes mellitus is a serious health problem that affects over 350 million individuals worldwide. Diabetic retinopathy (DR), which is the most common microvascular complication of diabetes, is the leading cause of new cases of blindness in working-aged ...
David S. Boyer +3 more
doaj +1 more source
The role of anti-vascular endothelial growth factor in diabetic macular edema
The continuous growing number of diabetic patients has caused a stable increase in the global prevalence of diabetes mellitus. One of the most common complications caused by diabetes is diabetic macular edema (DME).
Giovani Faustine, Ani Retno-Prijanti
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Molecular analysis of adenylyl cyclase: Bacillus anthracis edema factor exotoxin
Bacillus anthracis causes anthrax disease and exerts its deleterious effects by the release of three exotoxins, i.e. lethal factor, protective antigen and edema factor EF), a highly active calmodulin-dependent adenylyl cyclase (AC). However, conventional
Mohammed, Hesham Hamada Taha
core +1 more source
Diabetic macular edema: it is more than just VEGF [version 1; referees: 2 approved]
Diabetic macular edema is a serious visual complication of diabetic retinopathy. This article reviews the history of previous and current therapies, including laser therapy, anti-vascular endothelial growth factor agents, and corticosteroids, that have ...
Michael A. Singer +4 more
doaj +1 more source

