Results 51 to 60 of about 36,103 (144)
Bacillus anthracisEdema Toxin Impairs Neutrophil Actin-Based Motility [PDF]
Infection and Immunity, 2009 ABSTRACTInhalation anthrax results in high-grade bacteremia and is accompanied by a delay in the rise of the peripheral polymorphonuclear neutrophil (PMN) count and a paucity of PMNs in the infected pleural fluid and mediastinum. Edema toxin (ET) is one of the majorBacillus anthracisvirulence factors and consists of the adenylate cyclase edema factor ...
Sarah E, Szarowicz +5 more
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Cells, 2019 LiTCTP is a toxin from the Translationally Controlled Tumor Protein (TCTP) family identified in Loxosceles brown spider venoms. These proteins are known as histamine-releasing factors (HRF). TCTPs participate in allergic and anaphylactic reactions, which
Marianna Boia-Ferreira +12 more
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Anthrax Edema Toxin Inhibits Endothelial Cell Chemotaxis via Epac and Rap1 [PDF]
Journal of Biological Chemistry, 2007 Angiogenesis involves the assembly of endothelial cells into capillaries from a pre-existing vasculature. Because abnormal angiogenesis is a hallmark of many cancers, it is critical to find factors that control this process. Endothelial cells are enriched in the anthrax receptor; we therefore determined the effect of anthrax edema toxin (ET), an ...
Jia, Hong +5 more
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Membrane-Binding Mechanism of Clostridium perfringens Alpha-Toxin
Toxins, 2015 Clostridium perfringens alpha-toxin is a key mediator of gas gangrene, which is a life-threatening infection that manifests as fever, pain, edema, myonecrosis, and gas production. Alpha-toxin possesses phospholipase C and sphingomyelinase activities. The
Masataka Oda +3 more
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A viral nanoparticle with dual function as an anthrax antitoxin and vaccine. [PDF]
PLoS Pathogens, 2007 The recent use of Bacillus anthracis as a bioweapon has stimulated the search for novel antitoxins and vaccines that act rapidly and with minimal adverse effects. B.
Darly J Manayani +12 more
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Anthrax Toxin Characterization
Acta Medica, 2002 The anthrax toxin comprises three proteins. When they work together, they can kill humans, especially after spores of the bacteria have been inhaled.
Jiří Patočka, Miroslav Špliňo
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Noninvasive Imaging Technologies Reveal Edema Toxin as a Key Virulence Factor in Anthrax [PDF]
The American Journal of Pathology, 2011 Powerful noninvasive imaging technologies enable real-time tracking of pathogen-host interactions in vivo, giving access to previously elusive events. We visualized the interactions between wild-type Bacillus anthracis and its host during a spore infection through bioluminescence imaging coupled with histology.
Fabien, Dumetz +9 more
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Toxins, 2010 The Clostridium perfringens epsilon toxin, a select agent, is responsible for a severe, often fatal enterotoxemia characterized by edema in the heart, lungs, kidney, and brain. The toxin is believed to be an oligomeric pore-forming toxin.
Mark S. McClain +2 more
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A translational murine model of sub-lethal intoxication with Shiga toxin 2 reveals novel ultrastructural findings in the brain striatum. [PDF]
PLoS ONE, 2013 Infection by Shiga toxin-producing Escherichia coli causes hemorrhagic colitis, hemolytic uremic syndrome (HUS), acute renal failure, and also central nervous system complications in around 30% of the children affected. Besides, neurological deficits are
Carla Tironi-Farinati +5 more
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Toxins, 2011 Anthrax lethal toxin (LeTx) and edema toxin (EdTx) have been shown to alter hemodynamics in the rodent model, while LeTx primarily is reported to induce extensive tissue pathology.
Johnny W. Peterson +8 more
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