Results 101 to 110 of about 91,660 (282)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Fractional Q-Edge-Coloring of Graphs

Discussiones Mathematicae Graph Theory, 2013
An additive hereditary property of graphs is a class of simple graphs which is closed under unions, subgraphs and isomorphism. Let be an additive hereditary property of graphs.
Czap Július, Mihók Peter
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

On harmonious coloring of hypergraphs [PDF]

Discrete Mathematics & Theoretical Computer Science
A harmonious coloring of a $k$-uniform hypergraph $H$ is a vertex coloring such that no two vertices in the same edge have the same color, and each $k$-element subset of colors appears on at most one edge. The harmonious number $h(H)$ is the least number
Sebastian Czerwiński
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Strong Edge-Coloring Of Planar Graphs

Discussiones Mathematicae Graph Theory, 2017
A strong edge-coloring of a graph is a proper edge-coloring where each color class induces a matching. We denote by 𝜒's(G) the strong chromatic index of G which is the smallest integer k such that G can be strongly edge-colored with k colors. It is known
Song Wen-Yao, Miao Lian-Ying
doaj   +1 more source

Incidence Coloring—Cold Cases

Discussiones Mathematicae Graph Theory, 2020
An incidence in a graph G is a pair (v, e) where v is a vertex of G and e is an edge of G incident to v. Two incidences (v, e) and (u, f) are adjacent if at least one of the following holds: (i) v = u, (ii) e = f, or (iii) edge vu is from the set {e, f}.
Kardoš František, Maceková Mária, Mockovčiaková Martina, Sopena Éric, Soták Roman   +4 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Cartesian积与邻点可区别着色之间的关系(Relation between Cartesian product and adjacent vertex distinguishing coloring)

Zhejiang Daxue xuebao. Lixue ban, 2017
A proper k-edge coloring of a graph G is an assignment of k colors 1, 2, …, k to edges of G such that any two adjacent edges receive the different colors.
WANGGuoxing(王国兴)
doaj   +1 more source