Results 101 to 110 of about 4,602,540 (372)
Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
IEEE Access, 2018 Cloud computing is a paradigm that offers storage, computation, and software services on demand in the Cloud and far from end users. These services and computations are then extended to the Edge of the network with the Edge computing paradigm.
Rehmat Ullah +2 more
doaj +1 more source
Engineering a QoS Provider Mechanism for Edge Computing with Deep Reinforcement Learning
, 2019 With the development of new system solutions that integrate traditional cloud computing with the edge/fog computing paradigm, dynamic optimization of service execution has become a challenge due to the edge computing resources being more distributed and ...
Carpio, Francisco +3 more
core +1 more source
Molecular Oncology, EarlyView.Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane +16 more
wiley +1 more source
Security of intelligent edge computing:a survey
Dianxin kexue, 2018 With the rise of edge computing,more and more attentions have been paid to security issues of edge computing.The basic concepts,system architecture and the relationship between edge computing and other computing paradigms were introduced.Then the ...
Xingshuo AN +4 more
doaj +2 more sources
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source
Combining edge and cloud computing for mobility analytics
, 2017 Mobility analytics using data generated from the Internet of Mobile Things (IoMT) is facing many challenges which range from the ingestion of data streams coming from a vast number of fog nodes and IoMT devices to avoiding overflowing the cloud with ...
Cao, Hung +3 more
core +1 more source
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
Molecular Oncology, EarlyView.CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan +10 more
wiley +1 more source