Results 51 to 60 of about 240,296 (261)
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Edge contact forces in continuous media [PDF]
, 2006 1 Dipartimento di Matematica e Fisica, Universita Cattolica del Sacro Cuore, Via dei Musei 41, I-25121 Brescia, Italy m.degiovanni@dmf.unicatt.it 2 Dipartimento di Matematica, Universita di Brescia, Via Valotti 9, I-25133 Brescia, Italy alfredo.marzocchi@ing.unibs.it 3 Dipartimento di Matematica e Fisica, Universita Cattolica del Sacro Cuore, Via dei ...
Degiovanni, Marco +2 more
openaire +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Optimization of Contact Edge Profile for Minimizing Contact Pressure in a Press-fitted Shaft
MATEC Web of Conferences, 2018 In the shrink or press-fitted shafts such as railway axles, the rotor of a steam turbine or coupling, a high-stress concentration takes place in the close of contact edge due to relative slip between shaft and boss in a press-fitted shaft and this is a ...
Lee Dong-Hyung +3 more
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Disordered contacts can localize helical edge electrons [PDF]
Journal of Physics: Condensed Matter, 2019 Abstract It is well known that quantum spin Hall (QSH) edge modes being helical are immune to backscattering due to non-magnetic disorder within the sample. Thus, QSH edge modes are non-localized and show a vanishing Hall resistance along with quantized 2-terminal, longitudinal and non-local resistances even in ...
Arjun Mani, Colin Benjamin
openaire +3 more sources
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Jixie chuandong, 2009 The tooth edge contact of face gear drive with spur pinion isunavoidable. The meshing of face gear drive with spur pinion is investigated. A mathematical model and a constraint condition are developed, by which the contact points on tooth edge could be ...
沈云波, 方宗德, 赵宁, 魏冰阳
doaj