Results 81 to 90 of about 429,051 (306)
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Metric based resolvability of cycle related graphs
AIMS MathematicsIf a subset of vertices of a graph, designed in such a way that the remaining vertices have unique identification (usually called representations) with respect to the selected subset, then this subset is named as a metric basis (or resolving set).
Ali N. A. Koam
doaj +1 more source
The comparative study of resolving parameters for a family of ladder networks
AIMS Mathematics, 2022 For a simple connected graph $ G = (V, E) $, a vertex $ x\in V $ distinguishes two elements (vertices or edges) $ x_1\in V, y_1 \in E $ if $ d(x, x_1)\neq d(x, y_1). $ A subset $ Q_m\subset V $ is a mixed metric generator for $ G, $ if every two distinct
Mohra Zayed +3 more
doaj +1 more source
Hearing Delzant polytopes from the equivariant spectrum
, 2012 Let M^{2n} be a symplectic toric manifold with a fixed T^n-action and with a toric K\"ahler metric g. Abreu asked whether the spectrum of the Laplace operator $\Delta_g$ on $\mathcal{C}^\infty(M)$ determines the moment polytope of M, and hence by Delzant'
Dryden, Emily B. +2 more
core +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Uniquely identifying vertices and edges of a heptagonal snake graph using distance formulas
AIMS MathematicsConsider a city with a network of roads where surveillance cameras are positioned at key intersections. To uniquely determine the position of any car, the minimal number of cameras needed is determined by using the metric dimension of the network ...
Fozia Bashir Farooq +4 more
doaj +1 more source
Mixed metric dimension of graphs with edge disjoint cycles [PDF]
, 2021 Jelena Sedlar, Riste Škrekovski
openalex +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
On Resolvability- and Domination-Related Parameters of Complete Multipartite Graphs
Mathematics, 2022 Graphs of order n with fault-tolerant metric dimension n have recently been characterized.This paper points out an error in the proof of this characterization. We show that the complete multipartite graphs also have the fault-tolerant metric dimension n,
Sakander Hayat, Asad Khan, Yubin Zhong
doaj +1 more source
Molecular Oncology, EarlyView.The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations regarding the use of hormone replacement therapy (HRT), which is positioned as recommendation number 13 of the ECAC5.
Mangesh A. Thorat +18 more
wiley +1 more source