Results 1 to 10 of about 3,583,230 (197)

Correction to Pippa Smart’s viewpoint, “Dealing with difficult authors”. DOI:10.3897/ese.2020.e52201 [PDF]

open access: yesEuropean Science Editing, 2020
In this article the author’s competing interests were not declared. This has been corrected in the online article, DOI: 10.3897/ese.2020.e52201.
European Science Editing
doaj   +3 more sources

Comparing the accuracy and effectiveness of Wordvice AI Proofreader to two automated editing tools and human editors [PDF]

open access: yesScience Editing, 2022
Purpose Wordvice AI Proofreader is a recently developed web-based artificial intelligence-driven text processor that provides real-time automated proofreading and editing of user-input text.
Kevin Heintz   +2 more
doaj   +1 more source

Yearning for Verne. Twenty Thousand Leagues under the Seas “Restored” Edition [PDF]

open access: yesStudia Litterarum, 2023
In 2022, the university press Presses universitaires Blaise-Pascal (Clermont-Ferrand, France) published the first scholarly edition of one of the most prominent works by Jules Verne — Twenty Thousand Leagues Under the Seas. The publisher, ex-professor at
Kirill A. Chekalov
doaj   +1 more source

Homology directed correction, a new pathway model for point mutation repair catalyzed by CRISPR-Cas

open access: yesScientific Reports, 2022
Gene correction is often referred to as the gold standard for precise gene editing and while CRISPR-Cas systems continue to expand the toolbox for clinically relevant genetic repair, mechanistic hurdles still hinder widespread implementation.
Brett M. Sansbury   +5 more
doaj   +1 more source

Efficient Generation of P53 Biallelic Mutations in Diannan Miniature Pigs Using RNA-Guided Base Editing

open access: yesLife, 2021
The base editing 3 (BE3) system, a single-base gene editing technology developed using CRISPR/Cas9n, has a broad range of applications for human disease model construction and gene therapy, as it is highly efficient, accurate, and non-destructive.
Honghui Li   +13 more
doaj   +1 more source

RNA editing [PDF]

open access: yesFEMS Microbiology Reviews, 1999
The term RNA editing describes those molecular processes in which the information content is altered in an RNA molecule. To date such changes have been observed in tRNA. rRNA and mRNA molecules of eukaryotes, but not prokaryotes. The demonstration of RNA editing in prokaryotes may only be a matter of time, considering the range of species in which the ...
A, Brennicke, A, Marchfelder, S, Binder
openaire   +4 more sources

N 1-methyl-pseudouridine is incorporated with higher fidelity than pseudouridine in synthetic RNAs

open access: yesScientific Reports, 2022
In vitro transcribed synthetic messenger RNAs (mRNAs) represent a novel therapeutic modality. To overcome the inherent immunogenicity, as well as to increase the therapeutic efficacy of the molecules, uridine analogs—such as pseudouridine (Ψ) and N 1 ...
Tien-Hao Chen   +4 more
doaj   +1 more source

Construction of PIK3C3 Transgenic Pig and Its Pathogenesis of Liver Damage

open access: yesLife, 2022
As a member of the PIKs family, PIK3C3 participates in autophagy and plays a central role in liver function. Several studies demonstrated that the complete suppression of PIK3C3 in mammals can cause hepatomegaly and hepatosteatosis. However, the function
Jing Wang   +19 more
doaj   +1 more source

Rewriting Human History and Empowering Indigenous Communities with Genome Editing Tools. [PDF]

open access: yes, 2020
Appropriate empirical-based evidence and detailed theoretical considerations should be used for evolutionary explanations of phenotypic variation observed in the field of human population genetics (especially Indigenous populations). Investigators within
Fox, Keolu   +2 more
core   +2 more sources

Genome Editing

open access: yesMolecular Biotechnology, 2022
Recent advances in genome editing technologies have redefined our ability to probe and precisely edit the human genome and epigenome in vitro and in vivo. More specifically, RNA-guided CRISPR/Cas systems have revolutionized the field due to their simplicity in design and adaptability across biological systems.
Maura McGrail   +2 more
openaire   +5 more sources

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