Results 101 to 110 of about 9,410,480 (347)

Continuing medical education for general practitioners: a practice format

open access: yesPostgraduate medical journal, 2016
Introduction Our current knowledge-based society and the many actualisations within the medical profession require a great responsibility of physicians to continuously develop and refine their skills.
Lena Vannieuwenborg   +3 more
semanticscholar   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Universities in the Market for Continuing Higher Education [PDF]

open access: yes
The purpose of the paper is to explain why and how American universities have taken the lead in continuing education compared to their European counterparts.
Bettina Wentzel, Mark Oelmann
core  

New Research Provides Solutions to the Nursing Shortage: Improving Retention of Older and Experienced Nurses in the Workforce [PDF]

open access: yes, 2008
Outlines research findings on how early retirement contributes to the shortage of nurses and on incentives that help retain experienced nurses, including financial support for continuing education and redesigned work spaces, hours, and benefit ...

core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Perceptions, behaviours, barriers and needs of evidence-based medicine in primary care in Beijing: a qualitative study

open access: yesBMC Family Practice, 2019
Background Evidence-based medicine (EBM) is gradually being recognized worldwide as an important clinical skill and plays an important role in health care.
Yali Zhao   +6 more
doaj   +1 more source

Adaptation of the curriculum for the inclusion of learners with special education needs in selected primary schools in the Fort Beaufort District

open access: yesAfrican Journal of Disability, 2017
Background: There is need for ‘high-quality’ teachers who are equipped to meet the needs of all learners through provision of education for an inclusive society according to equal opportunities to all.
Toyin M. Adewumi   +3 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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