Results 91 to 100 of about 1,790,156 (306)

Investigating Continuing Professional Development Provided for Egyptian Higher Education Online Tutors [PDF]

, 2016
Tutors confront great challenges in their teaching practices, including changes in subject content, new instructional methods, changes laws and procedures and students’ needs.
Edwards, Julie-Ann, Ismail, Nashwa, Kinchin, Gary   +2 more
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

EXTRACORPOREAL RENAL SURGERY (LITERATURE REVIEW)

Сибирский онкологический журнал, 2017
Currently, along with the development of gravity blood surgery and transplantation, nephron-sparing surgery has become an established surgical treatment, particularly in situations in which preservation of renal parenchyma is critical.
R. I. Rasulov, V. V. Dvornichenko, A. A. Muratov   +2 more
doaj   +1 more source

Distance education at conventional universities in Germany [PDF]

, 2010
Germany’s educational system has undergone a series of transformations during the last 40 years. In recent years, marked increases in enrolment have occurred.
Kappel, Hans-Henning, Lehmann, Burkhard, Loeper, Joachim   +2 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Development of ODL in a newly industrialised country according to face-to-face contact, ICT, and e-readiness

International Review of Research in Open and Distributed Learning, 2013
A large number of unqualified and under-qualified in-service teachers are holding back socio-economical development in South Africa, a newly industrialized country.
J Marinda van Zyl, Christoffel Johannes Els, A Seugnet Blignaut   +2 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Universities in the Market for Continuing Higher Education [PDF]

The purpose of the paper is to explain why and how American universities have taken the lead in continuing education compared to their European counterparts.
Bettina Wentzel, Mark Oelmann
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Perceptions, behaviours, barriers and needs of evidence-based medicine in primary care in Beijing: a qualitative study

BMC Family Practice, 2019
Background Evidence-based medicine (EBM) is gradually being recognized worldwide as an important clinical skill and plays an important role in health care.
Yali Zhao, Xuexue Zhao, Yanli Liu, Yun Wei, Guanghui Jin, Shuang Shao, Xiaoqin Lu   +6 more
doaj   +1 more source