Results 101 to 110 of about 1,790,156 (306)

Adaptation of the curriculum for the inclusion of learners with special education needs in selected primary schools in the Fort Beaufort District

open access: yesAfrican Journal of Disability, 2017
Background: There is need for ‘high-quality’ teachers who are equipped to meet the needs of all learners through provision of education for an inclusive society according to equal opportunities to all.
Toyin M. Adewumi   +3 more
doaj   +1 more source

Online from Across the Pond [PDF]

open access: yes, 2017
When Hayley Carroll ’18 decided to return to college, an ocean separated her from the American system where she already had her higher-education start. But that didn’t stop her.
Davis, Laura
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Understanding Quantitative Circadian Regulations Are Crucial Towards Advancing Chronotherapy

open access: yesCells, 2019
Circadian rhythms have a deep impact on most aspects of physiology. In most organisms, especially mammals, the biological rhythms are maintained by the indigenous circadian clockwork around geophysical time (~24-h).
Debajyoti Chowdhury   +3 more
doaj   +1 more source

Enhancing Student Learning Experiences and Providing Value to the Agribusiness Industry by Building the Industry-Institution Interface [PDF]

open access: yes
This paper addresses agribusiness industry-institution interfaces, research-education linkages, and improving agribusiness education with opportunities such as agricultural students’ internships with agribusiness companies, conducting applied research ...
Devadoss, Stephen, Foltz, John C.
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Related Services Research Project to Support the Education of Students with Deaf-Blindness: Final Report. [PDF]

open access: yes, 1999
This Final Report documents the activities and products of the . Related Services Research Project to Support the Education of Students with Deafblindness, a four-year research project funded by the U.S.
Giangreco, Michael
core   +1 more source

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