Results 111 to 120 of about 8,255,634 (311)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

高敏感特質中高齡學習者面對數位學習壓力及疫情焦慮之學習滿意度與後疫情調適：復原力之中介效果 Learning Satisfaction and Post-Pandemic Adaptation in Highly Sensitive Middle-aged and Elderly Learners in the Face of Digital Learning Stress and Pandemic Anxiety

Journal of Research in Education Sciences
人口老化趨勢及近年疫情大流行加速了中高齡數位學習之推動與普及，在此環境改變下，對高敏感特質的長輩是一大考驗。本研究旨在探討高敏感特質之中高齡者於疫情變化使數位學習環境更為普及之狀況下，所產生的數位學習壓力、心理憂鬱及學習滿意度的關聯，並以復原力作為中介變項，最後亦探討疫情趨緩後中高齡者在後疫情之感受。本研究採用問卷調查法進行資料蒐集，研究工具為高敏感特質、疫情焦慮、數位學習壓力、憂鬱情緒量表、學習滿意度、復原力及後疫情正向感受等7份量表；以45歲以上有數位學習經驗的中高齡者為研究對象 ...
王雅鈴 Ya-Ling Wang, 張伶瑜 Lin-Yu Chang, 羅淇文 Chi-Wen Luo, 林郁文 Yu-Wen Lin   +3 more
doaj   +1 more source

The Minnesota Plan for the Continuing Education of Women

, 1961
Pamphlet; Source: University Archives Collection 1158, Information files,"Women's Continuing Education Program -1969, Folder 1Women's Continuing Education Program. (1961). The Minnesota Plan for the Continuing Education of Women.
Women's Continuing Education Program
core  

Is There A Future for Research in University Continuing Education?

, 1999
University-based Continuing Education units have become primarily focused on market driven programs at a time when market demand for continuing education has attracted a great deal of competition in that field.
Selman, Mark
core   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Clinical case of liver transplantation in a kidney transplant recipient with hepatocellular cancer and сoronary artery disease

Вестник трансплантологии и искусственных органов
Objective: organ transplantation is a highly effective and often the only possible definitive treatment for terminal diseases, significantly improving patient survival and quality of life.
A. V. Shabunin, Z. A. Bagatelia, P. A. Drozdov, A. G. Komarova, S. A. Bliznyuk, G. S. Michailyants, E. Yu. Astapovich, S. A. Astapovich, V. A. Tsurkan, Yu. I. Mitchenko, P. E. Pazenko   +10 more
doaj   +1 more source

Survey of Distance Learning Provision in Continuing Health Professional Education in Canada

, 2003
In Canada, the trend is towards greater use of distance learning technologies in the provision of continuing professional education in the health professions.
Curran, Vernon, Curran, Fran, Fleet, Lisa   +2 more
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Mediational effect analysis of childhood emotional abuse on prodromal psychotic symptoms in self-taught examination students

Scientific Reports
It has been shown that childhood trauma is associated with an increased risk of prodromal psychotic symptoms. However, research on the prevalence of prodromal psychotic symptoms among self-taught examination students and the relationship with childhood ...
Yanchi Wang, Dandan Wu, Jinjun Wang, Yuan Chen, Xiang Chen, Wen Shi, Qing Xia, Jian Gu   +7 more
doaj   +1 more source

The Minnesota Plan for the Continuing Education of Women Newsletter

, 1962
Source: University Archives Collection 1158, Information files,"Women's Continuing Education Program" -1969, Folder 1Women's Continuing Education Program. (1962). The Minnesota Plan for the Continuing Education of Women Newsletter.
Women's Continuing Education Program
core