Results 71 to 80 of about 20,645,859 (299)

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Higher Education [PDF]

open access: yes
During the last five years higher education research in Germany seems to be in a significant upturn. This is a side effect partly of the obvious boom of empirical educational research in general and partly of the reform movement that has affected the ...
Andrä Wolter
core  

SOA services in higher education [PDF]

open access: yes, 2008
Service Oriented Architecture (SOA) is a recent architectural framework for distributed software system development in which software components are packaged as Services.
Joy, Mike   +1 more
core  

Comparative results of the state exit exams in the medical degree during five academia years

open access: yesRevista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2020
Background: the state exit exams are the certification of the competence of the graduates. Analyzing the results obtained in this type of assessment is useful to detect deficiencies in the teaching-learning process.Objective: to describe, making a ...
Norkis Sánchez-Alonso   +4 more
doaj  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Modus Operandi: Irrigation of the Modified Eloesser Flap in Heterogeneous Suppurative Lung Pathologies

open access: yesJournal of Chest Surgery, 2021
Background: Refractory empyemas with collapsed lung and persistent bronchopleural fistulas pose significant problems to thoracic surgeons and impose a substantial burden in terms of morbidity and mortality.
Rajkamal Vishnu   +3 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Learning roadmaps for Higher Education [PDF]

open access: yes, 2007
An integrated platform for the support of teaching activities as been developed and deployed at the Aveiro Norte Polytechnic School of the University of Aveiro.
Duarte, A. Manuel de Oliveira   +2 more
core   +1 more source

A abordagem do envelhecimento na formação universitária dos profissionais de saúde: uma revisão integrativa

open access: yesRevista Brasileira de Geriatria e Gerontologia
O objetivo deste artigo foi identificar, com base na literatura, como a saúde do idoso e o envelhecimento têm sido abordados na formação universitária dos profissionais de saúde e o que vem sendo considerado relevante nesta temática.
Claudia Reinoso Araujo de Carvalho   +1 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

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