Results 71 to 80 of about 663,893 (316)

Understanding and managing change in educational organizations [PDF]

open access: yes
The deterministic perspective, which views contemporary educational organizations as classical cause-and-effect systems that can be easily controlled and digitized, no longer provides the necessary support and solutions to these organizations and their ...
Çobanoğlu, Fatma
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Communication and the Process of Educational Change

open access: yesAcademic Medicine, 1998
In this chapter, the authors describe the role of communication in the process of curricular reform at the eight schools that participated in The Robert Wood Johnson Foundation's "Preparing Physicians for the Future: Program in Medical Education." The collective experience of these eight schools suggests that despite its general neglect in the ...
E F, Dannefer   +2 more
openaire   +4 more sources

Paving the way for sustainable educational change: Reconceptualizing what it means to make educational changes that last [PDF]

open access: yes, 2020
This position paper provides an alternative theoretical framework of sustainable second-order educational change. Here, sustainability refers to: 1) substantial changes made that affect the core of educators’ everyday practice; 2) a longitudinal process ...
Hubers, Mireille D.
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Teacher Education Reforms between Higher Education and General Education Transformations in South- Eastern Europe: Reviewing the Evidence and Scoping the Issues

open access: yesCenter for Educational Policy Studies Journal, 2012
The present paper considers reforms and developments in teacher education in South-Eastern European countries as part of overall reforms in higher education, and in light of changes in general education that impact teachers and their preparation.
Nataša Pantić
doaj   +1 more source

Educational strategies for small island states [PDF]

open access: yes, 1993
This publication describes the significance, relevance, and practical implications for educational planning of insularity and small size. Its empirical basis is drawn primarily from the Caribbean and South Pacific regions.
Atchoarena, David
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Can Qualitative Research Inform Policy Implementation? Evidence and Arguments from a Developing Country Context

open access: yesForum: Qualitative Social Research, 2003
How can qualitative research inform policy implementation? This article hopes to shed some light on this complex yet relevant issue and locates this inquiry in a transitional South African context. I intend to qualitatively reveal the local teacher voice,
Brigitte Smit
doaj  

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