Results 51 to 60 of about 3,499,995 (260)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Graphical dynamic trends for earthquake incidence response of plan-asymmetric systems [PDF]

, 2015
A Graphical Dynamic model is derived to describe the directional earthquake response of two-ways plan-asymmetric systems, which retains the insightful educational evidence of traditional graphical static methods and the accuracy of computational methods ...
Faggella, Marco, Gigliotti, R, Mezzacapo, G, Spacone, E.   +3 more
core   +2 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Metabolic Syndrome Screening in Seriously Mentally Ill Patients: A Quality Improvement Project [PDF]

, 2016
A Project Submitted in Partial Fulfillment of the Requirements for the Degree of MASTER OF SCIENCE in Nursing ScienceSeriously mentally ill patients who are taking second-generation antipsychotics have a high risk of metabolic complications ...
Moreno, Annabel
core  

Educational interventions to improve people's understanding of key concepts in assessing the effects of health interventions: a systematic review [PDF]

, 2018
Background Health information is readily accessible but is of variable quality. General knowledge about how to assess whether claims about health interventions are trustworthy is not common, so people’s health decisions can be ill-informed, unnecessarily
Chalmers, Iain, Cusack, Leila, Del Mar, Chris B., Gibson, Elizabeth, Hoffmann, Tammy C.   +4 more
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Evaluation Methods for Prevention Education

Academic Medicine, 2000
The knowledge, skills, and attitudes associated with prevention cut across clinical disciplines. Thus, they are often subsets of disciplines not otherwise present in the traditional curriculum (e.g., epidemiology or statistics) or considered the province of many disciplines (e.g., risk reduction or cancer screening).
A V, Blue, J J, Barnette, K J, Ferguson, D R, Garr   +3 more
openaire   +3 more sources

Methods of teaching educational sector "Social Science" [PDF]

, 2017
У робочій навчальній програмі подано мету, зміст та завдання вивчення дисципліни "Методика навчання освітньої галузі "Суспільствознавство""В рабочей учебной программе представлены цели, содержание и задачи изучения дисциплины "Методика обучения ...
Вишнівська, Наталія Володимирівна
core  

Preliminary assessment of the computer-based Taenia solium educational program ‘The Vicious Worm’ on knowledge uptake in primary school students in rural areas in eastern Zambia [PDF]

, 2018
Objective: The zoonotic helminth Taenia solium is endemic in Zambia, causing human (taeniasis and (neuro)cysticercosis) and pig (porcine cysticercosis) diseases with high health, social and economic burdens.
Alexander, Ash, Bardosh, Birbeck, Braae, Bulaya, Carabin, Dorny, Ertel, Ertel, Gabriël, Garcia, Johansen, Mwanga, Mwape, Mwape, Mwape, Mwidunda, Ngowi, Pondja, Sarti, Sarti, Thys, Thys, Torgerson, WHO, Wohlgemut   +26 more
core   +2 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source