Results 61 to 70 of about 427,659 (248)

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Principal's Leadership as An Educational Supervisor In Improving The Quality of Teaching and Learning

Jurnal Inovasi Pendidikan dan Sains
This study aims to analyze the strategic role of the principal as an educational supervisor in improving the sustainable quality of teaching and learning at Tabgha Mulia School, Batam.
Ratna Sagala, Tubagus Pamungkas, Ramdhani Ramdhani   +2 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Implementation of School Culture Based on Pancasila Values at the Elementary School Level in Muara Tiga District, Pidie Regency

Jurnal Inovasi Pendidikan dan Sains
This study aims to analyze the leadership of elementary school principals, teachers’ behavior, and obstacles in applying the practical values of Pancasila deliberative at the elementary school level in Muara Tiga District, Pidie Regency.
Hendriani Hendriani, Najmuddin Najmuddin, Siraj Siraj   +2 more
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Web-Based Interactive Learning Multimedia with a Constructivist Approach for Elementary School English Lessons

Jurnal Media dan Teknologi Pendidikan
The low English learning outcomes of fourth-grade elementary students due to difficulties in understanding time-related vocabulary highlight the urgency of a developmental study aimed at designing and evaluating the validity, practicality, and ...
Tiara Arifah, L. Heny Nirmayani, I Made Tegeh   +2 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Animated Video Learning Media for the IPAS Subject on Plant Body Parts for Fourth Grade Elementary School Students

Jurnal Media dan Teknologi Pendidikan
Learning of IPAS (Science, Environment, and Social Studies) in elementary schools is often hindered by the lack interactive media that can simplify abstract concepts such as the parts of plant bodies. This leads to low motivation and understanding among
Fauzatul Imamah, I Kadek Suartama, Adrianus I Wayan Ilia Yuda Sukmana   +2 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

An Analysis of the Impact of Differentiated Instruction on Academic Achievement Among Grade X Students in Vocational Education

Jurnal Inovasi Pendidikan dan Sains
This study aims to investigate the effectiveness of implementing differentiated instruction in improving student learning outcomes in Informatics for Grade X students at a vocational high school.
Dedi Aviadi, Albert Efendi Pohan, Tubagus Pamungkas   +2 more
doaj   +1 more source