Results 21 to 30 of about 97,533 (239)

Redox regulation of KV7 channels through EF3 hand of calmodulin

open access: yeseLife, 2023
Neuronal KV7 channels, important regulators of cell excitability, are among the most sensitive proteins to reactive oxygen species. The S2S3 linker of the voltage sensor was reported as a site-mediating redox modulation of the channels. Recent structural
Eider Nuñez   +10 more
doaj   +1 more source

Mutation of the pseudo‐EF‐hand of calbindin D9k into a normal EF‐hand [PDF]

open access: yesEuropean Journal of Biochemistry, 1991
The two Ca2+‐binding sites in calbindin D9k, a protein belonging to the calmodulin superfamily of intracellular proteins, have sligtly different structure. The C‐terminal site (amino acids 54–65) is a normal EF‐hand as in the other proteins of the calmodulin superfamily, while the N‐terminal site (amino acids 14–27) contains two additional amino acids,
C, Johansson   +4 more
openaire   +2 more sources

Assembling a hand-held trichotillometer and determination of epilation force in normal individuals

open access: yesIndian Dermatology Online Journal, 2017
Aim: To assemble a simple, inexpensive hand-held trichotillometer and to determine the epilation force (EF) required to pluck the anagen hair and telogen hair from four regions of the scalp in healthy volunteers. Materials and Methods: A simple hand-held
Kumaresan Muthuvel   +2 more
doaj   +1 more source

Autism-associated mutation in Hevin/Sparcl1 induces endoplasmic reticulum stress through structural instability

open access: yesScientific Reports, 2022
Hevin is a secreted extracellular matrix protein that is encoded by the SPARCL1 gene. Recent studies have shown that Hevin plays an important role in regulating synaptogenesis and synaptic plasticity.
Takumi Taketomi   +7 more
doaj   +1 more source

Characterization of the 1st and 2nd EF-hands of NADPH oxidase 5 by fluorescence, isothermal titration calorimetry, and circular dichroism

open access: yesChemistry Central Journal, 2012
Background Superoxide generated by non-phagocytic NADPH oxidases (NOXs) is of growing importance for physiology and pathobiology. The calcium binding domain (CaBD) of NOX5 contains four EF-hands, each binding one calcium ion.
Wei Chin-Chuan   +7 more
doaj   +1 more source

EF-hand proteins in onychophorans as compared to tardigrades and other ecdysozoans

open access: yesJournal of Limnology, 2013
To learn more about the regulation of muscle contraction in the structural and functionally different muscles in Ecdysozoa, we have analysed the four EF-hand proteins calmodulin (CaM), troponin C (TnC), essential myosin light chain (eMLC) and regulatory ...
Thiruketheeswaran Prasath   +2 more
doaj   +1 more source

Getting the right grasp on executive function

open access: yesFrontiers in Psychology, 2014
Executive Function (EF) refers to important socio-emotional and cognitive skills that are known to be highly correlated with both academic and life success. EF is a blanket term that is considered to include self-regulation, working memory, and planning.
Claudia L R Gonzalez   +6 more
doaj   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

Modulating uranium binding affinity in engineered calmodulin EF-hand peptides: effect of phosphorylation. [PDF]

open access: yesPLoS ONE, 2012
To improve our understanding of uranium toxicity, the determinants of uranyl affinity in proteins must be better characterized. In this work, we analyzed the contribution of a phosphoryl group on uranium binding affinity in a protein binding site, using ...
Romain Pardoux   +6 more
doaj   +1 more source

Duplex Stainless Steel Laser‐Surface Textured: Stability in Brine Solution

open access: yesAdvanced Engineering Materials, EarlyView.
Controlled laser‐surface treatment (LST) of duplex DSS2205 steel is performed to increase its stability in brine solution under cyclic electrochemical assays. The superior protection with respect to flat and smooth panels is attributed to the presence of FeCr2O4 as the main protective oxide layer in the LST surface, after corrosion tests. The stability
Mohammad Rezayat   +5 more
wiley   +1 more source

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