Results 71 to 80 of about 1,437,766 (290)

Causality and energy conditions in nonlinear electrodynamics

Journal of High Energy Physics
For the general theory of nonlinear electrodynamics (NLED) we prove that causality implies both the Dominant Energy Condition (DEC) and, surprisingly, the Strong Energy Condition (SEC).
Jorge G. Russo, Paul K. Townsend
doaj   +1 more source

Effective Field Theories for the Casimir Effect at Finite Temperature [PDF]

arXiv, 2001
We discuss corrections to the Casimir effect at finite temperature and effective field theory. Recently, it has been shown that effective field theories can reproduce radiative corrections to the Casimir energy calculated in full QED. We apply effective field theory methods at finite temperature and reproduce the Casimir free energy.
arxiv  

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1985-1998, December 2022., 2022
Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy.
Aina Calls, Abel Torres‐Espin, Marc Tormo, Laura Martínez‐Escardó, Núria Bonet, Ferran Casals, Xavier Navarro, Víctor J. Yuste, Esther Udina, Jordi Bruna   +9 more
wiley   +1 more source

Dualities of self-dual nonlinear electrodynamics

Journal of High Energy Physics
For any causal nonlinear electrodynamics theory that is “self-dual” (electromagnetic U(1)-duality invariant), the Legendre-dual pair of Lagrangian and Hamiltonian densities L H $$ \left\{\mathcal{L},\mathcal{H}\right\} $$ are constructed from functions ℓ
Jorge G. Russo, Paul K. Townsend
doaj   +1 more source

Effective Field Theory description of Phantom Fields [PDF]

arXiv, 2018
In this work I show that a simple Field Theory on a non trivial gauge background may behave as a phantom field and contribute to an effective $w<-1$ state equation fluid contribution to cosmology.
arxiv  

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Recognizing early MRI signs (or their absence) is crucial in diagnosing metachromatic leukodystrophy

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1999-2009, December 2022., 2022
Abstract Objectives Metachromatic leukodystrophy (MLD) has characteristic white matter (WM) changes on brain MRI, which often trigger biochemical and genetic confirmation of the diagnosis. In early or pre‐symptomatic disease stages, these typical MRI changes might be absent, hampering early diagnosis.
Daphne H. Schoenmakers, Shanice Beerepoot, Ingeborg Krägeloh‐Mann, Saskia Elgün, Benjamin Bender, Marjo S. van der Knaap, Nicole I. Wolf, Samuel Groeschel   +7 more
wiley   +1 more source

Generalized T T ¯ $$ T\overline{T} $$ -like deformations in duality-invariant nonlinear electrodynamic theories

Journal of High Energy Physics
This study introduces a high-order perturbation methodology to categorize two primary solution types within duality-invariant nonlinear electrodynamic theories, adhering to the differential self-duality criterion.
H. Babaei-Aghbolagh, Song He, Hao Ouyang
doaj   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source