Results 61 to 70 of about 14,162,835 (267)
Results in Control and OptimizationThis study presents a mathematical model to investigate the patterns of transmission in lymphatic filariasis. The model considers chronic, acute, and asymptomatic individuals and integrates key control strategies.
Mussa A. Stephano +2 more
doaj +1 more source
Modeling present and future climate risk of dengue outbreak, a case study in New Caledonia
Environmental Health, 2022 Background Dengue dynamics result from the complex interactions between the virus, the host and the vector, all being under the influence of the environment.
Noé Ochida +7 more
doaj +1 more source
Estimating the effective reproduction number of the 2019-nCoV in China [PDF]
, 2020 Abstract We estimate the effective reproduction number for 2019-nCoV based on the daily reported cases from China CDC. The results indicate that 2019-nCoV has a higher effective reproduction number than SARS with a comparable fatality rate.
Cao Z +6 more
europepmc +2 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Spatially explicit effective reproduction numbers from incidence and mobility data
Proceedings of the National Academy of Sciences, 2023 Current methods for near real-time estimation of effective reproduction numbers from surveillance data overlook mobility fluxes of infectors and susceptible individuals within a spatially connected network (the metapopulation). Exchanges of infections among different communities may thus be misrepresented unless explicitly measured
Cristiano Trevisin +7 more
openaire +2 more sources
Estimation and worldwide monitoring of the effective reproductive number of SARS-CoV-2 [PDF]
eLife, 2020 The effective reproductive number R e is a key indicator of the growth of an epidemic. Since the start of the SARS-CoV-2 pandemic, many methods and online dashboards have sprung up to monitor this number through time.
Jérémie Scire +7 more
openaire +5 more sources
Epidemic Data Analysis of Three Variants of COVID-19 Spread in Indonesia
Jurnal Ilmu Komputer dan Informasi, 2022 Three variants of COVID-19 had been found in Indonesia. A control strategy may rely on the transmission rate of the variant. This study aims to investigate how the variants spread in Indonesia by computing a basic and effective reproduction number on the
Inna Syafarina +3 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reflections on two years estimating effective reproduction numbers
, 2022 31 March, in just under a weeks time, will mark the last day we are producing global national and subnational Rt estimates and nowcasts at https://epiforecasts.io/covid/posts/global/ - more than 2 years after we published the first set of estimates. This is a good opportunity to reflect on what we have learned from this, what went well and what went ...
Sam Abbott, Sebastian Funk
openaire +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source