Results 1 to 10 of about 18,481,212 (402)

Improved prediction of fungal effector proteins from secretomes with EffectorP 2.0

Molecular Plant Pathology, 2018
Plant-pathogenic fungi secrete effector proteins to facilitate infection. We describe extensive improvements to EffectorP, the first machine learning classifier for fungal effector prediction. EffectorP 2.0 is now trained on a larger set of effectors and
Jana Sperschneider, Peter N Dodds, Donald M Gardiner   +2 more
exaly   +2 more sources

Effector CD8 T cells dedifferentiate into long-lived memory cells

Nature, 2017
Memory CD8 T cells that circulate in the blood and are present in lymphoid organs are an essential component of long-lived T cell immunity. These memory CD8 T cells remain poised to rapidly elaborate effector functions upon re-exposure to pathogens, but ...
Ben Youngblood, Andrew Karellas, Keith D Paulsen   +2 more
exaly   +2 more sources

Transcriptional control of effector and memory CD8+ T cell differentiation

Nature Reviews Immunology, 2012
Susan M Kaech, Weiguo Cui
exaly   +2 more sources

A somato-cognitive action network alternates with effector regions in motor cortex

Nature, 2023
Functional MRI studies across ages show that the classic homunculus of the motor cortex in humans is in fact discontinuous, alternating with action control-linked regions termed the somato-cognitive action network.
Evan M. Gordon, R. Chauvin, A. N. Van, Aishwarya Rajesh, A. Nielsen, Dillan J. Newbold, Charles J. Lynch, Nicole A. Seider, S. Krimmel, Kristen M. Scheidter, Julia S. Monk, Ryland L. Miller, Athanasia Metoki, D. Montez, Annie Zheng, I. Elbau, Thomas J. Madison, T. Nishino, Michael J. Myers, S. Kaplan, Carolina Badke D’Andrea, D. Demeter, Matthew Feigelis, J. Ramirez, Ting Xu, D. Barch, C. Smyser, C. Rogers, Jan Zimmermann, K. Botteron, J. Pruett, Jon T. Willie, P. Brunner, J. Shimony, B. Kay, Scott A. Marek, S. Norris, C. Gratton, C. Sylvester, Jonathan D. Power, C. Liston, D. Greene, J. Roland, S. Petersen, M. Raichle, Timothy O. Laumann, D. Fair, N. Dosenbach   +47 more
semanticscholar   +1 more source

FIRE Mimics a 14-3-3–Binding Motif to Promote Phytophthora palmivora Infection

Molecular Plant-Microbe Interactions, 2023
The oomycete Phytophthora palmivora infects a wide range of tropical crops worldwide. Like other filamentous plant pathogens, it secretes effectors to colonize plant tissues.
Edouard Evangelisti, Alex Guyon, Liron Shenhav, Sebastian Schornack   +3 more
doaj   +1 more source

A simple and sensitive flow cytometric assay for the determination of the cytotoxic activity of human natural killer cells [PDF]

, 1990
A new, simple and sensitive flow cytometric assay for the determination of the cytotoxic activity of human natural killer cells is described. The assay is based on the use of two fluorochromes. The target cell population is stained with one fluorochrome (
Garritsen, Henk S.P., Graft, Marja van, Greve, Jan, Grooth, Bart G. de, Radosevic, Katarina   +4 more
core   +10 more sources

High-Quality Nuclear Genome and Mitogenome of Bipolaris sorokiniana LK93, a Devastating Pathogen Causing Wheat Root Rot

Molecular Plant-Microbe Interactions, 2023
Bipolaris sorokiniana, one of the most devastating hemibiotrophic fungal pathogens, causes root rot, crown rot, leaf blotching, and black embryos of gramineous crops worldwide, posing a serious threat to global food security.
Wanying Zhang, Qun Yang, Lei Yang, Haiyang Li, Wenqing Zhou, Jiaxing Meng, Yanfeng Hu, Limin Wang, Ruijiao Kang, Honglian Li, Shengli Ding, Guotian Li   +11 more
doaj   +1 more source

The Globodera pallida SPRYSEC Effector GpSPRY-414-2 That Suppresses Plant Defenses Targets a Regulatory Component of the Dynamic Microtubule Network

Frontiers in Plant Science, 2018
The white potato cyst nematode, Globodera pallida, is an obligate biotrophic pathogen of a limited number of Solanaceous plants. Like other plant pathogens, G.
Yuanyuan Mei, Yuanyuan Mei, Kathryn M. Wright, Annelies Haegeman, Lander Bauters, Amalia Diaz-Granados, Aska Goverse, Godelieve Gheysen, John T. Jones, John T. Jones, Sophie Mantelin   +10 more
doaj   +1 more source

Bioinformatic Detection of Positive Selection Pressure in Plant Pathogens: The Neutral Theory of Molecular Sequence Evolution in Action

Frontiers in Microbiology, 2020
The genomes of plant pathogenic fungi and oomycetes are often exposed to strong positive selection pressure. During speciation, shifts in host range and preference can lead to major adaptive changes.
Mark C. Derbyshire
doaj   +1 more source

A Functional Analysis on the Interspecies Interaction between Mouse LFA-1 and Human Intercellular Adhesion Molecule-1 at the Cell Level

Frontiers in Immunology, 2017
The interaction between intercellular adhesion molecules (ICAM) and the integrin leukocyte function-associated antigen-1 (LFA-1) is crucial for the regulation of several physiological and pathophysiological processes like cell-mediated elimination of ...
David Núñez, David Núñez, David Núñez, Laura Comas, Laura Comas, Laura Comas, Pilar M. Lanuza, Pilar M. Lanuza, Diego Sánchez-Martinez, Diego Sánchez-Martinez, Marta Pérez-Hernández, Marta Pérez-Hernández, Elena Catalán, María Pilar Domingo, Adrián Velázquez-Campoy, Adrián Velázquez-Campoy, Adrián Velázquez-Campoy, Julián Pardo, Julián Pardo, Julián Pardo, Julián Pardo, Eva M. Gálvez, Eva M. Gálvez   +22 more
doaj   +1 more source