Results 41 to 50 of about 14,265 (225)
Measuring Apoptotic Cell Engulfment (Efferocytosis) Efficiency [PDF]
, 2019 Efferocytosis is the process of recognizing and removing dead and dying cells, performed by a variety of phagocytic cells including macrophages. It has recently been shown that liver X receptor (LXR) signaling in macrophages regulates the expression of ...
Matthew C. Gage, Gage, MC
core +2 more sources
Immunity, Inflammation and Disease, 2023 Efferocytosis can resolve airway inflammation and enhance airway tolerance in allergic asthma. While previous work has reported that progranulin (PGRN) regulated macrophage efferocytosis, but it is unclear whether PGRN‐mediated efferocytosis is ...
Qi Huang +9 more
doaj +1 more source
unannotated efferocytosis images
, 2023 unannotated efferocytosis ...
Bérénice A. Benayoun (10152083) +2 more
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Efferocytosis of Pathogen-Infected Cells [PDF]
Frontiers in Immunology, 2017 The prompt and efficient clearance of unwanted and abnormal cells by phagocytes is termed efferocytosis and is crucial for organism development, maintenance of tissue homeostasis, and regulation of the immune system. Dying cells are recognized by phagocytes through pathways initiated via "find me" signals, recognition via "eat me" signals and down ...
Karaji, N, Sattentau, Q
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Boosting efferocytosis in alveolar space using BCG vaccine to protect host against influenza pneumonia. [PDF]
PLoS ONE, 2017 Efferocytosis by alveolar phagocytes (APs) is pivotal in maintenance of lung homeostasis. Increased efferocytosis by APs results in protection against lethal acute lung injury due to pulmonary infections whereas defective efferocytosis by APs results in ...
Sanjay Mukherjee +5 more
doaj +1 more source
Efferocytosis in health and disease
Nature Reviews Immunology, 2019 The clearance of apoptotic cells by professional and non-professional phagocytes - a process termed 'efferocytosis' - is essential for the maintenance of tissue homeostasis. Accordingly, defective efferocytosis underlies a growing list of chronic inflammatory diseases. Although much has been learnt about the mechanisms of apoptotic cell recognition and
Amanda C. Doran +2 more
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The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Modulation of Macrophage Efferocytosis in Inflammation [PDF]
Frontiers in Immunology, 2011 A critical function of macrophages within the inflammatory milieu is the removal of dying cells by a specialized phagocytic process called efferocytosis ("to carry to the grave"). Through specific receptor engagement and induction of downstream signaling, efferocytosing macrophages promote resolution of inflammation by (i) efficiently engulfing dying ...
Korns, Darlynn +4 more
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Effects of efferocytosis on fibrosis
, 2022 Billions of cells die every day to maintain homeostasis, and dying cells including apoptotic cells are removed rapidly by phagocytes. This process is called as efferocytosis.
Hyunjin Park
core
Nogo-B impairs efferocytosis in monocyte-derived macrophages and exacerbates septic liver injury
JHEP ReportsBackground & Aims: Efferocytosis is essential for maintaining tissue homeostasis and resolving inflammation, but this process is compromised during sepsis.
Weizhe Zhong +15 more
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