Results 101 to 110 of about 8,924,877 (409)
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
How individualism and collectivism relate to team performance, team cohesion, and collective efficacy in a multilevel analysis : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Psychology at Massey University, Manawatū, New Zealand [PDF]
, 2016 Individual-level individualism (IND) and collectivism (COL), team performance, and team cohesion were investigated as predictors of collective efficacy using Hierarchical Linear Modelling (HLM).
Edwards, Lydia Lucy
core
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla +5 more
wiley +1 more source
Pharmacological Potential of Cinnamic Acid and Derivatives: A Comprehensive Review
PharmaceuticalsCinnamic acid, an organic acid naturally occurring in plants of the Cinnamomum genus, has been highly valued for its medicinal properties in numerous ancient Chinese texts.
Yu Tian +7 more
doaj +1 more source
Mothers who are Refugees: An analysis of trauma, social support, and parenting efficacy. [PDF]
, 2017 The following exploratory correlational study examined the relationships among trauma severity, social support, and parenting self-efficacy in a sample of mothers who are refugees living in Vermont.
Papka, Sophia Valeria
core +1 more source
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Innate Lymphoid Cells: Regulators of Gut Barrier Function and Immune Homeostasis
Journal of Immunology Research, 2019 Innate lymphoid cells (ILCs), identified in the early years of this century as a new class of leukocyte family unlike the B or T lymphocytes, play a unique role bridging the innate and adaptive immune responses in mucosal immunity.
Hui Fan +8 more
doaj +1 more source
The social dimension of teaching: trust and teachers' efficacy beliefs [PDF]
, 2012 Educational research increasingly highlights teachers’ trust in other school members to support school functioning. Besides, teachers’ efficacy beliefs are considered to be crucial in their functioning.
Van Houtte, Mieke, Van Maele, Dimitri
core +1 more source
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source