Results 251 to 260 of about 427,575 (339)

The Pivotal Role of GR‐CAR Pathway in Fetal Programming of Hepatic Cytochrome P450 3A Alteration in Adulthood

Advanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) persistently upregulates hepatic CYP3A1/CYP2B1 in offspring via glucocorticoid receptor (GR) activation. In vivo and in vitro studies show GR promotes P300/CBP binding to the constitutive androstane receptor (CAR) promoter, sustaining histone acetylation (H3K9/K27ac) and enhancing CYP expression. The GR–CAR pathway
Xiaoxiang Sun, Jie Liu, E Xiang, Xia Li, Xuerong Yan, Yuxi Wang, Feng Li, Hao Kou, Hui Wang, Yu Guo   +9 more
wiley   +1 more source

Strain-dependent contribution of the AcrAB-TolC efflux pump to <i>Klebsiella pneumoniae</i> physiology. [PDF]

Microbiology (Reading)
Bhogal K, Clough B, Emmerson C, Organ A, Chen Y, Buckner MM, Alav I.   +6 more
europepmc   +1 more source

Sabatier‐Adjusted d‐Band Centers of Scalable Asymmetric Iron Sites toward Dynamic Nonradical Network for Fast Mineralization with Low‐Amount Oxidant

Advanced Science, EarlyView.
Asymmetric iron single‐atom catalysts with Sabatier‐adjusted d‐band centers overcome the inherent limitations of peroxymonosulfate (PMS) activation by establishing a synergistic nonradical pathway network, achieving exceptional pollutant mineralization (≈85%) at only one‐tenth conventional PMS dosage.
Yue Chen, Xunheng Jiang, Zhiyu Pan, Zhenjie Li, Chaohuang Chen, Can Li, Chenghui Luo, Shengkun Zhang, Daohui Lin, Xinhua Xu, Jiang Xu   +10 more
wiley   +1 more source

Diabetic kidney disease macrophage cholesterol efflux: a revolution from metabolism to immune. [PDF]

Front Endocrinol (Lausanne)
Wang J, Cai Y, Feng Y, Zhu Q.
europepmc   +1 more source

Components of forest soil CO2 efflux as estimated from 14C values of SOM

, 2012
Mirco Rodeghiero, Robbert Hakkenberg, Galina Churkina, Cristina Martinez, Thomas Scholten, A. Cescatti   +5 more
openalex   +1 more source

Biomimetic membrane-coated nanoparticles for targeted synergistic therapy of homocysteine-induced atherosclerosis: Dual modulation of cholesterol efflux and reactive oxygen species scavenging

Hongyan Ding, Yi Liu, Tongtong Xia, Huiping Zhang, Yinju Hao, Bin Liu, Yideng Jiang   +6 more
openalex   +1 more source

Computational Study Reveals the Molecular Mechanism of the Interaction between the Efflux Inhibitor PAβN and the AdeB Transporter from Acinetobacter baumannii

, 2017
Shirin Jamshidi, J. Mark Sutton, Khondaker Miraz Rahman   +2 more
openalex   +1 more source

Alkaline Phosphatase‐Activated NIR‐II AIEgens Nanosystem for Surgical and Postoperative Closed‐Loop Therapy of Advanced Osteosarcoma

Advanced Science, EarlyView.
This study designed a tumor microenvironment‐responsive AIEgen nanoparticle for near‐infrared photoimmunotherapy, which inhibits primary tumors and metastasis by promoting pyroptosis and suppressing aerobic glycolysis. ABSTRACT In advanced osteosarcoma, tumor invasion often prevents complete resection, and immunotherapy is limited by the tumor's ...
Kaiyuan Liu, Ruotong Li, Li Zhang, Hengli Lu, Binhui Yang, Qian Hu, Yining Tao, Haoran Mu, Jing Han, Pengfei Zan, Jiakang Shen, Dongqing Zuo, Hongsheng Wang, Wei Sun, Xingjun Zhu   +14 more
wiley   +1 more source

Traditional Chinese medicine monomers: a new strategy against diabetic kidney disease by regulating cholesterol efflux. [PDF]

Front Nutr
Wu C, Sun J, Shi J, Li Z, An Y, Zhu H, Wang L, Liu P.   +7 more
europepmc   +1 more source

Inflammatory corpuscle AIM2 facilitates macrophage foam cell formation by inhibiting cholesterol efflux protein ABCA1 [PDF]

Shujiang Zhuo, Sufei Song, Chaoyi Wang, Zhe Wang, Ming Zhang, Daobin Lin, Kaili Chen   +6 more
openalex   +1 more source