Results 281 to 290 of about 427,575 (339)

Integrative review on Acinetobacter baumannii as a multidrug-resistant pathogen: resistance mechanisms and therapeutic perspectives in the context of nosocomial infections. [PDF]

Rev Soc Bras Med Trop
Lima PHM, Lopes CF, Freire JPC, Feliciano LD, Amorim RCO, Mota ML, Cirqueira FF, Lemos FFB, Pedroso SHSP, Melo FF.   +9 more
europepmc   +1 more source

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

Advanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen   +2 more
wiley   +1 more source

Targeting Multidrug Resistance in Cancer: Impact of Retinoids, Rexinoids, and Carotenoids on ABC Transporters. [PDF]

Int J Mol Sci
Čižmáriková M, Háziková V, Michalková R, Franko O, Lešková B, Homolya AD, Gabzdilová J, Takáč P.   +7 more
europepmc   +1 more source

Nanozymes for Energy and Environmental Sustainability

Advanced Science, EarlyView.
At present, the widely used nanozymes are oxidoreductase and hydrolase, which have proved to have great application prospects in energy and environment. ABSTRACT Nanozymes have shown remarkable promise in addressing pressing challenges in energy and environmental sustainability.
Xiaoqi Li, Jinxing Chen, Shaojun Dong
wiley   +1 more source

In-vitro Assessment of BCRP-Mediated Efflux of Antiseizure Medications in Human Blood-Brain Barrier Cell Model. [PDF]

J Biochem Mol Toxicol
Bora S, Paul PR, Kukal S, Mishra MK, Hasija Y, Kukreti R.   +5 more
europepmc   +1 more source

A Sirtuin‐1‐Targeted Gene‐Activating Tetrahedral DNA Attenuates Bladder Fibrosis by Restoring Mitophagy in Fibroblasts via the SIRT1‐FOXO3‐BNIP3 Axis

Advanced Science, EarlyView.
The SIRT1‐targeted saRNA‐delivering tetrahedral DNA (TSA) treatment effectively upregulates SIRT1 expression, which subsequently promotes FOXO3A deacetylation. This deacetylation event relieves FOXO3A's transcriptional repression on the BNIP3 gene, thereby initiating PINK1‐PARKIN‐dependent mitophagy.
Wei Wang, Ran Yan, Lede Lin, Lei Xiang, Xiaozhi Xia, Liao Peng, Xiaoshuai Gao, Jiawei Chen, Yang Xiong, Liang Zhou, Yunfeng Lin   +10 more
wiley   +1 more source

Genomic characterization and comparative analysis of multidrug-resistant Escherichia coli ST361 from urban wetland. [PDF]

BMC Microbiol
Srijith L, Sivakumar V, Sivanandham G, Sridharan KS, Paul A, Warrier S, Perumal K.   +6 more
europepmc   +1 more source

Nicotine causes prostaglandin efflux from isolated perfused rat lung [proceedings].

, 1979
Berry Cn, Hoult, J M Littleton, Moore Pk, Umney Nd   +4 more
openalex   +1 more source

Resilient Calvarial Bone Marrow Supports Retinal Repair in Type 2 Diabetes

Advanced Science, EarlyView.
Skull bone (calvarium) marrow in diabetic mice stay structurally intact and keeps making blood cells, unlike the bone marrow of the leg bones. The skull marrow is exposed to cerebrospinal fluid (CSF), which contains protective molecules called oxysterols.
Bright Asare‐Bediako, Sergio Li Calzi, Julia G. Behnsen, Ram Prasad, Magdalena Blaszkiewicz, Yvonne Adu‐Rutledge, Robert F. Rosencrans, Jason L. Floyd, Ashley Rennhack, Denise Stanford, Anna Lin, Todd A. Lydic, Carl M. Sheridan, Michael E. Boulton, Kristy L. Townsend, Julia V. Busik, Maria B. Grant   +16 more
wiley   +1 more source