Results 91 to 100 of about 997,958 (247)
Advanced Science, EarlyView.LDHA‐driven lactate production in mesenchymal glioma stem cells promotes p300‐dependent H3K18 lactylation, activates USP30 transcription, and stabilizes MBOAT2 to remodel phosphatidylethanolamines toward ferroptosis‐resistant PE‐MUFA species. Disrupting this metabolic–epigenetic–lipid circuit enhances ferroptosis and sensitizes glioblastoma to ...
Zong Miao +13 more
wiley +1 more source
Chronic high vibration issue of a Condensate Pump [PDF]
, 2022 Case StudiesChronic high vibration issue was being observed on a critical condensate pump. Although this motor driven pump is a standby unit, however, in case the running pump has a breakdown and the motor pump is unavailable, the Ammonia Plant will trip.
Bukhari, Syed M. Haseeb +1 more
core
Advanced Science, EarlyView.This work reports the in situ fabrication of Escherichia coli@covalent organic frameworks (E. coli@COFs) in phosphate‐buffered saline. The COFs form an exoskeleton on E. coli, protecting intracellular β‐glucosidase (Ssbgl) while enhancing mass transfer.
Fengmei Liu +6 more
wiley +1 more source
Molecular mechanism of transition-state inhibitors of bacterial antibiotic efflux pumps
npj Antimicrobials and ResistanceIn many Gram-negative bacteria such as Escherichia coli and Klebsiella pneumoniae, the AcrAB-TolC efflux pump is central to multidrug resistance. We report the development of BDM91531, a nanomolar pyridylpiperazine inhibitor that potentiates the activity
Clara Börnsen +12 more
doaj +1 more source
, 2016 Case StudyCase Study 16: In the modern pump industry, processed fluids are characterized by a wide spectrum of viscosity values. An unpredicted variation of actual process fluid properties, including viscosity, may lead to unexpected pump performance ...
Cicatelli, Giancarlo, Schiavello, Bruno
core +1 more source
Advanced Science, EarlyView.Global dissemination of tmexCD‐toprJ across bacterial hosts and ecological niches is accompanied by its convergence with blaKPC, blaNDM, and mcr on mobile plasmids. Recombination and acquisition of resistance modules generate distinct multidrug resistant plasmid architectures, facilitating the emergence and spread of high‐risk bacterial populations ...
Kaiwen Song +9 more
wiley +1 more source
Data reduction problems using a 3 holes directional pressure probe to investigate mean flow characteristics in the vaneless gap between impeller and diffuser radial pump [PDF]
, 2013 Among several different measurement techniques that have been already performed and presented in a radial impeller pump model including PIV, a directional pressure probe has been used to obtain mean velocity field and stagnation pressure between impeller
DAZIN, Antoine +4 more
core +1 more source
An Intravesical Akkermansia muciniphila‐Based Chemo‐Immunotherapeutic Platform for Bladder Cancer
Advanced Science, EarlyView.Pasteurized Akkermansia muciniphila is engineered into an intravesical F127/doxorubicin platform that couples localized chemotherapy with immune remodeling. By inducing apoptosis, ferroptosis, and immunogenic cell death, this chemo‐immunotherapeutic system enhances dendritic‐cell maturation, antigen cross‐presentation, and tumor‐specific CD8+ T‐cell ...
Rongkang Li +11 more
wiley +1 more source
, 2019 A 4-cyano-3-methylisoquinoline inhibitor of Plasmodium falciparum growth targets the sodium efflux pump ...
Tania De Koning-Ward (13096974) +18 more
core
Overcoming Drug Resistance by Paclitaxel Resistance in Triple‐Negative Breast Cancer
Advanced Science, EarlyView.In the murine triple‐negative breast cancer (TNBC) model, chemotherapy effectively increases tumor neoantigen burden (TNB). Here, the study constructs a liposomal nanovaccine using antigens derived from in vitro chemotherapy‐treated paclitaxel‐resistant TNBC 4T1 cells.
Bo Chen +10 more
wiley +1 more source