Results 21 to 30 of about 997,958 (247)

Clinically Approved Drugs Inhibit the Staphylococcus aureus Multidrug NorA Efflux Pump and Reduce Biofilm Formation

open access: yesFrontiers in Microbiology, 2019
Staphylococcus aureus has acquired resistance to antibiotics since their first use. The S. aureus protein NorA, an efflux pump belonging to the major facilitator superfamily (MFS), contributes to resistance to fluoroquinolones (e.g., ciprofloxacin ...
Saskia Zimmermann   +11 more
doaj   +1 more source

Evaluation of silibinin as an efflux pump inhibitor in Bacillus subtilis

open access: yes, 2021
ALTINIŞIK F, ATAŞ B, Avci FG. Evaluation of silibinin as an efflux pump inhibitor in Bacillus subtilis. International Journal of Secondary Metabolite. 2021;8(2):104-112.Antibiotic resistance has become a global health problem for humankind.
ATAŞ, Başak   +2 more
core   +1 more source

An alternative physiological role for the EmhABC efflux pump in Pseudomonas fluorescens cLP6a [PDF]

open access: yes, 2011
Background Efflux pumps belonging to the resistance-nodulation-division (RND) superfamily in bacteria are involved in antibiotic resistance and solvent tolerance but have an unknown physiological role.
Foght, J.M., Adebusuyi, A.A.
core   +1 more source

Efflux Pump Activity and Mutations Driving Multidrug Resistance in Acinetobacter baumannii at a Tertiary Hospital in Pretoria, South Africa

open access: yesInternational Journal of Microbiology, 2021
Acinetobacter baumannii (A. baumannii) has developed several resistance mechanisms. The bacteria have been reported as origin of multiple outbreaks. This study aims to investigate the use of efflux pumps and quinolone resistance-associated genotypic ...
Noel-David Nogbou   +9 more
doaj   +1 more source

Numerical simulation of flow field in water-pump sump and inlet suction pipe [PDF]

open access: yes, 2010
There are several important considerations in the design of a suction supply sump. It is imperative that the amount of turbulence and entrained air be kept to a minimum.
BOIS, Gérard   +2 more
core   +1 more source

Effect of Vitamin K3 Inhibiting the Function of NorA Efflux Pump and Its Gene Expression on Staphylococcus aureus

open access: yesMembranes, 2020
Resistance to antibiotics has made diseases that previously healed easily become more difficult to treat. Staphylococcus aureus is an important cause of hospital-acquired infections and multi-drug resistant.
Saulo R. Tintino   +14 more
doaj   +1 more source

Efficacy of "HLE"—a multidrug efflux-pump inhibitor—as a disinfectant against surface bacteria [PDF]

open access: yes, 2018
We evaluated the efficacy of a new disinfectant product, HLE, to inhibit multiple species of planktonic and biofilm bacterial cultures. The HLE disinfectant comprised of EDTA, lactic acid and hydrogen peroxide, and our data indicated that the ...
Antonio Gálvez   +18 more
core   +4 more sources

Fundamentals of Centrifugal Pump and System Interaction [PDF]

open access: yes, 2011
Short CoursePumps are an integral part of your industry, yet engineers, operators, and maintenance technicians are seldom fully trained to handle the pump problems they encounter daily.
Volk, Michael, Volk, Mike
core   +1 more source

A truncated AdeS kinase protein generated by ISAba1 insertion correlates with tigecycline resistance in Acinetobacter baumannii. [PDF]

open access: yesPLoS ONE, 2012
Over-expression of AdeABC efflux pump stimulated continuously by the mutated AdeRS two component system has been found to result in antimicrobial resistance, even tigecycline (TGC) resistance, in multidrug-resistant Acinetobacter baumannii (MRAB ...
Jun-Ren Sun   +8 more
doaj   +1 more source

Identification and evolution of drug efflux pump in clinical Enterobacter aerogenes strains isolated in 1995 and 2003. [PDF]

open access: yesPLoS ONE, 2008
BackgroundThe high mortality impact of infectious diseases will increase due to accelerated evolution of antibiotic resistance in important human pathogens.
Jacqueline Chevalier   +5 more
doaj   +1 more source

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