Results 211 to 220 of about 147,157 (321)

GLP‐1 Receptor Agonists in Metabolic Dysfunction‐Associated Steatotic Liver Disease: Bridging Hepatic and Cardiovascular Outcomes

Chronic Diseases and Translational Medicine, EarlyView.
Endogenous GLP‐1 and exogenous GLP‐1 RAs activate GLP‐1R‐expressing vagal afferents in the portal vein, projecting to the nucleus tractus solitarius (NTS). This input engages brainstem–hypothalamic circuits that regulate metabolic homeostasis. Hypothalamic efferent vagal output to the liver suppresses lipogenesis, enhances triglyceride export, and ...
Gabriel Amorim Moreira Alves, Masatoki Teranishi, Rajendranandini Majumdar, Fazal Khan, Mohan Dodeja, Ana Claudia Teixeira de Castro Gonçalves Ortega, Marco Acerboni, Arosh S. Perera Molligoda Arachchige, Frank James   +8 more
wiley   +1 more source

Mutations in the proximal binding site and F-loop of AdeJ confer resistance to efflux pump inhibitors. [PDF]

Antimicrob Agents Chemother
Saral Sariyer A, Leus IV, Tambat R, Farjana M, Olvera M, Rukmani SJ, Sariyer E, Smith JC, Parks JM, Walker JK, Zgurskaya HI.   +10 more
europepmc   +1 more source

From Food Waste to Valorized Nanomaterials: Sustainable Green Synthesis and Biomedical Applications

ChemFoodChem, EarlyView.
Food waste‐derived biomolecules act as natural reducing and stabilizing agents for the green synthesis of functional NPs with applications in antimicrobial systems, food packaging, biomedical technologies, and environmental remediation. ABSTRACT Food waste is a global issue, with billions of tons discarded and unutilized annually, causing economic ...
Siddhraj Rajput, Gautam Priyadarshi, Santosh Kumar Sahu, Bhakti Patel, Avni Thakker, Sherzodbek Tashbaev, Gulomov Gafurjon Shavkatbek Ugli, Dipak Kumar Sahoo, Ashish Patel   +8 more
wiley   +1 more source

Exploring novel amides as efflux pump inhibitors for overcoming antibiotic resistance in multidrug-resistant <i>Pseudomonas aeruginosa</i>. [PDF]

Iran J Microbiol
Ullah F, Ali M, Niaz F, Khan IA, Khan SW, Khan M, Ishaq R, Manan A, Yu Y, Ilyas M.   +9 more
europepmc   +1 more source

Waste activated sludge high‐rate treatment of septage: Biodegradability studies and contact phase trials towards a cleaner environment

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract The waste activated sludge high‐rate (WASHR) process, developed in our previous study, is used for septic wastewater treatment. This high‐rate contact stabilization pre‐treatment uses typical waste streams found in wastewater treatment plants to reduce a portion of the loadings on the main treatment trains.
Arman Shirali, Melody Blythe Johnson, Mehrab Mehrvar   +2 more
wiley   +1 more source

Microplastics and nanoplastics in water: Improving removal in wastewater treatment plants with alternative coagulants

The Canadian Journal of Chemical Engineering, EarlyView.
The contaminant removal performance of a conventional coagulant, alum, and alternative coagulants, aluminium chlorohydrate (ACH) and ACH + pDADMC, are compared in challenging wastewater treatment conditions (pH >7.8). The interactions of each coagulant with a negatively charged surface are depicted based on quartz crystal microbalance with dissipation ...
Sinan Abi Farraj, Mathieu Lapointe, Rafael S. Kurusu, Nathalie Tufenkji   +3 more
wiley   +1 more source

An undergraduate experimental research program, involving the screening of efflux pump inhibitors, to improve student research skills in biomedical science. [PDF]

BMC Med Educ
Zong G, Zhang P, Wang Y, Han J, Wang L, Pan J, Pang J, Cao G, Fu J.   +8 more
europepmc   +1 more source

Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodeling

Developmental Dynamics, EarlyView.
Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff, Sandra Schrenk, Kara Soroko, Chhiring Sherpa, Ashok Arasu, Damien Reynaud, Elisa Boscolo   +6 more
wiley   +1 more source

NorA Efflux Pump Inhibitors: Expanding SAR Knowledge of Pyrazolo[4,3-c][1,2]benzothiazine 5,5-Dioxide Derivatives. [PDF]

Arch Pharm (Weinheim)
Cernicchi G, Di Gregorio A, Felicetti T, Rampacci E, Casari G, Armeni T, Romaldi B, Zefaj E, Passamonti F, Massari S, Manfroni G, Barreca ML, Tabarrini O, Vignaroli C, Sabatini S.   +14 more
europepmc   +1 more source

Hydrophobic eutectic solvent‐engineered membranes for highly permeable, selective, and antifouling pharmaceutical removal from municipal wastewater

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Single‐step incorporation of a hydrophobic deep eutectic solvent (HDES) into polyethersulfone ultrafiltration membranes via non‐solvent induced phase separation creates selective, antifouling membranes for pharmaceutical removal. The HDES nanodomains enhance permeability, electrostatic interactions, and adsorption affinity, enabling efficient and ...
Anjali Goyal, Tarek Lemaoui, Mahendra Kumar, Ahmad S. Darwish, Ali Zerriouh, Fawzi Banat, Hassan A. Arafat, Shadi W. Hasan, Inas M. AlNashef   +8 more
wiley   +1 more source