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Small Multidrug Resistance Efflux Pumps
2016Small multidrug resistance (SMR) transporters confer resistance to a variety of quaternary cation compound antimicrobials. These secondary active transporters are the smallest known transporters and have been demonstrated to function within the membrane.
Denice C. Bay, Raymond J. Turner
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Efflux pump activity in Enchytraeidae
2019Enchytraeids are ecologically relevant soil organisms, which play an important role in organic matter decomposition and soil bioturbation. They live in close contact with the pore water fraction of soil which makes them vulnerable to xenobiotics exposure.
Hackenberger Kutuzović, Davorka +3 more
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Bacterial efflux pump inhibition.
Current opinion in investigational drugs (London, England : 2000), 2005Drug efflux is recognized as a clinically relevant mechanism of antimicrobial drug resistance in selected species of bacteria. Membrane-based polypeptides belong to distinct protein superfamilies, the members of which are related by structural characteristics, mechanism of action and energy source for the transport process.
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Strategies to Overcome Efflux Pumps
2009Intestinal efflux pumps such as P-glycoprotein play a significant role in altering the absorption of a wide range of drugs. Anticancer agents, antibiotics, antivirals, calcium channel blockers, immunosuppressive agents, peptide drugs and several other therapeutic compounds have been reported to be substrates of one or more transmembrane efflux ...
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Antibiotic resistance and efflux pumps
2019The main purpose of this manuscript is to review the resistance against antibiotics and efflux pumps, one of the mechanisms important in resistance against antibiotics. As a definition, the resistance against antibiotics is accepted as the capability of a microorganism to resist the activity of antimicrobials, which were successfully used to kill the ...
ALTINÖZ, Eda, ALTUNER, Ergin Murat
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Update on Multidrug Resistance Efflux Pumps in Acinetobacter spp.
Antimicrobial Agents and Chemotherapy, 2021Vanessa Kornelsen, Ayush Kumar
exaly
Natural Product as Efflux Pump Inhibitors Against MRSA Efflux Pumps: An Update
2022Pallavi Ahirrao +2 more
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