Results 241 to 250 of about 86,304 (284)

Correction: Analysis of relative genes expression and mutation of pstB and efpA efflux pumps in Mycobacterium simiae isolates from suspected tuberculosis patients by using quantitative Real-time PCR. [PDF]

BMC Microbiol
Hashemzadeh M, Hasanvand M, Montazeri EA.   +2 more
europepmc   +1 more source

Identification of Compounds With Potential Dual Inhibitory Activity Against Drug Efflux Pumps in Resistant Cancer Cells and Bacteria: Protocol for a Systematic Review.

JMIR Res Protoc
Beleva E, Diukendjieva A, Pajeva I, Tsakovska I.   +3 more
europepmc   +1 more source

Analysis of relative genes expression and mutation of pstB and efpA efflux pumps in Mycobacterium simiae isolates from suspected tuberculosis patients by using quantitative Real-time PCR. [PDF]

BMC Microbiol
Hashemzadeh M, Hasanvand M, Montazeri EA.   +2 more
europepmc   +1 more source

Efflux pumps and microbial biofilm formation

Infection, Genetics and Evolution, 2023
Biofilm-related infections are resistant forms of pathogens that are regarded as a medical problem, particularly due to the spread of multiple drug resistance. One of the factors associated with biofilm drug resistance is the presence of various types of efflux pumps in bacteria.
Hossein Samadi Kafil
exaly   +3 more sources

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Antibiotic efflux pumps

Biochemical Pharmacology, 2000
Active efflux from procaryotic as well as eucaryotic cells strongly modulates the activity of a large number of antibiotics. Effective antibiotic transport has now been observed for many classes of drug efflux pumps. Thus, within the group of primary active transporters, predominant in eucaryotes, six families belonging to the ATP-binding cassette ...
F, Van Bambeke, E, Balzi, P M, Tulkens
openaire   +2 more sources

Efflux pump inhibitors: new updates

Pharmacological Reports, 2020
The discovery of antibiotics ought to have ended the issue of bacterial infections, but this was not the case as it has led to the evolution of various mechanisms of bacterial resistance against various antibiotics. The efflux pump remains one of the mechanisms through which organisms develop resistance against antibiotics; this is because organisms ...
Manaf AlMatar, Osman Albarri, Essam A. Makky, Fatih Köksal   +3 more
openaire   +2 more sources

Mycobacterial efflux pumps and chemotherapeutic implications

International Journal of Antimicrobial Agents, 2003
The demonstration of the existence of active efflux pumps in mycobacteria raises the question of whether or not these can increase in number and activity rendering wild-type mycobacteria increasingly resistant to a given antibiotic. This could be a mechanism by which mutated resistant strains become better fit to the selective environment ...
Miguel Viveiros, Clara Leandro, Leonard Amaral   +2 more
exaly   +3 more sources

New-generation efflux pump inhibitors

Expert Review of Clinical Pharmacology, 2008
The development of novel efflux pump inhibitors is an emerging and challenging research field. Besides the use of such excipients in cancer therapy, efflux pump inhibitors are gaining increasing interest with regards to drug delivery. In particular, inhibition of efflux pumps located in the intestine and the blood-brain barrier offers promising ...
Martin, Werle, Hirofumi, Takeuchi, Andreas, Bernkop-Schnürch   +2 more
openaire   +2 more sources

Leishmaniasis: efflux pumps and chemoresistance

International Journal of Antimicrobial Agents, 2003
Resistance of parasitic protozoa such as Leishmania to therapeutic drugs continues to escalate in developing countries. Treatment programs for human leishmaniasis are still based on pentavalent antimonials but resistance to these compounds has been a persistent problem.
Clara, Leandro, Lenea, Campino
openaire   +2 more sources