Results 31 to 40 of about 1,204 (125)

Fatigue in Myasthenia Gravis: Recent Advances and Emerging Concepts

Muscle &Nerve, Volume 74, Issue S1, Page S24-S30, September 2026.
ABSTRACT Fatigue is a common, often disabling symptom in myasthenia gravis (MG), distinct from muscle fatigability, and strongly associated with reduced quality of life. This narrative review examines current evidence on fatigue in MG, its patient impact, and future research directions. Earlier studies, mostly small and heterogeneous, reported a highly
Yvonne J. M. Campman, Martijn R. Tannemaat, Annabel M. Ruiter, Sarah Hoffmann   +3 more
wiley   +1 more source

Resolution of anti-GAD-associated autoimmune encephalitis in patients treated with efgartigimod

Frontiers in Neurology
IntroductionTemporal lobe epilepsy (TLE) is a significant clinical phenotype of anti-glutamic acid decarboxylase (GAD)-associated disease, which is characterized by disturbances in GABAergic inhibitory neurotransmission.
Min Chen, Zhuajin Bi, Wenzhong Kang, Ruihan Liu, Liu Hongbo, Yan Jiang, Qun Wang, Qun Wang, Qun Wang   +8 more
doaj   +1 more source

Clinical Characteristics and Treatment Management of Seronegative Myasthenia Gravis: A Systematic Review of the Literature

Muscle &Nerve, Volume 74, Issue S1, Page S76-S83, September 2026.
ABSTRACT Seronegative myasthenia gravis (SNMG) is characterized by the absence of detectable autoantibodies against known MG targets, despite clinical and electrophysiological evidence of a postsynaptic neuromuscular junction disorder. The aim of this systematic review was to better define clinical features, diagnostic clues and treatment outcome of ...
Massimiliano Ugo Verza, Mattia Schiavolin, Francesca Beretta, Sara Cornacchini, Antonio Lotti, Gregorio Spagni, Valentina Damato   +6 more
wiley   +1 more source

Clinical efficacy of efgartigimod combined with intravenous methylprednisolone in the acute phase of neuromyelitis optica spectrum disorders

Orphanet Journal of Rare Diseases
Background Neuromyelitis Optica Spectrum Disorders (NMOSD) comprise a group of autoimmune-mediated, inflammatory, demyelinating central nervous system diseases caused by aquaporin-4 (AQP4) IgG autoantibodies.
Wenjing Yang, Pei Chen, Jiaxuan Guo, Huiyu Feng, Xin Huang   +4 more
doaj   +1 more source

Optimization of the Cell‐Based Assay Methodology to Study Degradation of Acetylcholine Receptors (Antigenic Modulation) by Antibodies From Myasthenia Gravis Patients

Muscle &Nerve, Volume 74, Issue S1, Page S150-S158, September 2026.
ABSTRACT Introduction/Aims Degradation of cell‐surface acetylcholine receptors (AChRs) by antigenic modulation is a key pathogenic mechanism of myasthenia gravis (MG) autoantibodies, yet standard assays primarily detect antibody binding rather than functional effects.
Peng Du, Marina Mané‐Damas, Fien M. Verhamme, Mahan Moshir, Peter Ulrichts, Barbie Machiels, Mario Losen, Pilar Martinez‐Martinez   +7 more
wiley   +1 more source

Bullous Pemphigoid Disease Area Index Pruritus, Activity, and Damage During Biologic Therapy in Bullous Pemphigoid: An International Dual‐Center Study

The Journal of Dermatology, Volume 53, Issue 9, Page 1353-1357, September 2026.
ABSTRACT Biologic therapies targeting Type 2 inflammation are increasingly used in bullous pemphigoid, yet the relationship between pruritus and distinct disease domains remains incompletely defined. We conducted a retrospective international dual‐center study of 25 patients with bullous pemphigoid treated with dupilumab, omalizumab, or tralokinumab ...
Ruggero Cascio Ingurgio, Angela Alfano, Aalia Syed, Luigi Gargiulo, Alessandra Narcisi, Antonio Costanzo, Dedee F. Murrell   +6 more
wiley   +1 more source

Efgartigimod in the treatment of Guillain-Barré syndrome: case report

Frontiers in Immunology
Guillain–Barré syndrome (GBS) is a rare neurological disorder characterized by muscle weakness and paralysis. Although the exact etiology remains unclear, the current standard treatments include intravenous immunoglobulin (IVIG) and plasma exchange (PLEX)
Min Deng, Zhaohong Kong, Yan Wang, Xufeng Wang, Tao Li   +4 more
doaj   +1 more source

Nipocalimab in Early‐Onset Severe Hemolytic Disease of the Fetus and Newborn

Pediatric Discovery, EarlyView.
Aditya Hemedra Bhatt, Somashekhar Marutirao Nimbalkar, Dipen Vasudev Patel, Reshma Kushal Pujara   +3 more
wiley   +1 more source

Case Report: A myasthenia gravis patient complicated with renal failure was effectively treated with efgartigimod

Frontiers in Immunology
Myasthenia gravis (MG) is a neuromuscular junction disorder clinically characterized by fluctuating muscle weakness, in which some patients with respiratory muscle weakness are at risk of progressing to myasthenia gravis crisis and respiratory failure ...
Jia Ke, Qi Zhao, Na Wang, Bei Zhang, Jin-Quan Hu   +4 more
doaj   +1 more source

Idiopathic Orbital Inflammation Masquerading as Relapse of Seronegative Juvenile Myasthenia Gravis: A Case Report

Journal of Paediatrics and Child Health, EarlyView.
Wenhao Duan, Yanqing Zhang, Wensha Nie, Hongchao Jiang, Huiping Wang   +4 more
wiley   +1 more source