Results 61 to 70 of about 12,119 (270)

Rewiring NADH Metabolism Through NQO1‐Mediated Redox Cycling for Targeted Follicular Lymphoma Therapy

Advanced Science, EarlyView.
ABSTRACT Follicular lymphoma (FL) remains an incurable B‐cell malignancy with high relapse rates, and conventional therapies are often limited by significant toxicity, highlighting the need for novel treatments. We identified that FL exhibits markedly low expression of NAD(P)H: quinone oxidoreductase 1 (NQO1), a key enzyme required for activating ...
Jinxing Zhang, Ziqi Wang, Ye Weng, Yulin Fu, Yuelong Jiang, Beilin Zhuang, Wenzi Zeng, Xiangchun Zhang, Bing Xu, Jie Zha, Hongjun Zhuang   +10 more
wiley   +1 more source

Epigallocatechin-3-gallate (EGCG) inhibits the migratory behavior of tumor bronchial epithelial cells-6

, 2011
And 7.5 μg/ml (C, F) of EGCG. In presence of EGCG at 5 (B) or 7.5 μg/ml (C), we observed a decrease in the number of cells expressing vimentin. At higher magnification (D, E, F), alterations of the vimentin network were observed: less expression and more
Myriam Polette (58028), Magali Milliot (58025), Christine Terryn (58026), Philippe Birembaut (58029), Jérôme Cutrona (58027), Salma Hazgui (58022), Jean-Marie Zahm (27105), Arnaud Bonnomet (58023), Béatrice Nawrocki-Raby (58024)   +8 more
core   +1 more source

Comparison and Assessment of Anti‐Inflammatory and Antioxidant Capacity Between EGCG and Phosphatidylcholine‐Encapsulated EGCG

Journal of Cosmetic Dermatology
ABSTRACT Aim To compare and evaluate the differences between EGCG and phosphatidylcholine‐encapsulated EGCG in terms of their anti‐inflammatory and antioxidant capacities. Methods In this study, transdermal absorption
Yuan, Minjia, Hu, Lili, Zhu, Cuicui, Li, Qi, Tie, Hang, Ruan, Haihua, Wu, Tao, Zhang, Hongyang, Xu, Liang   +8 more
openaire   +2 more sources

Orchestrated Engineered Polyphenol‐Peptide Condensates Coupled With β‐GP Reverses Diabetic Osteoporosis by Remodeling Mitophagy

Advanced Science, EarlyView.
A multifunctional β‐GP@EGCG‐E7 nanoplatform is engineered by polyphenol–peptide condensation and phosphate loading. Bone‐targeted delivery, antioxidant and anti‐inflammatory activity, and mitophagy restoration are integrated in one system, enabling protection of osteoblasts and endothelial cells and promoting bone regeneration under diabetic ...
Xiuyun Xu, Meiqin Zhang, Ting Wu, Erfan Wei, Andrei Y. Hancharou, Zeying Wang, Zijuan Wang, Letian Lv, Likun Wu, Xingtong Pan, Qiyue Zhu, Xinyi Dong, Hao Liu, Yongsheng Zhou   +13 more
wiley   +1 more source

The Potency Of PLGA-Encapsulated Epigallocatechin Gallate (EGCG) As Adjuvant Therapy For Chronic Kidney Disease [PDF]

Chronic kidney disease (CKD) prevalence keeps increasing worldwide and being particular concern due to its morbidity and mortality. However, current CKD therapy are known to be economically costly and not necessarily provide better outcomes ...
Dinda Dwi Purwati, Dinda, Arifa Mustika, Arifa, Alyaa Ulaa Dhiya Ul Haq, Alyaa, Deandra Maharani Widiatmaja, Deandra   +3 more
core   +1 more source

Heat Shock Protein 90: From Molecular Chaperone Function to Therapeutic Targeting in Malignancies

Advanced Science, EarlyView.
In this review, an integrated conceptual framework linking HSP90's molecular chaperone functions to its pathological roles in cancer is proposed. HSP90 serves as a central node that integrates oncogenic signaling, buffers proteotoxic stress, maintains cancer stem cell plasticity, and shapes tumor‐immune interactions, all of which converge to drive ...
Beibei Zhang, Xinxin Zou, Jiansong Zhou, Qinmiao Sun, Dahua Chen   +4 more
wiley   +1 more source

Green tea as a cosmetic agent for skin aging: A scoping review [PDF]

Avicenna Journal of Phytomedicine
Objective: Tea is known to have antioxidant and anti-inflammatory properties. Also, skin care products often contain antioxidant compounds that help protect the skin from free radicals that cause premature aging.
Ratih Febrinasari, Benedictus Benedictus, Kenneth Tan, Yasmine Mardhiati, Salsabilla Putri, Syaiful Choiri, Dinar Wahyuni   +6 more
doaj   +1 more source

The Effect of Vitamin C Addition on Epigallocatechin Gallate (EGCG) Stability in Green Tea Solution

Jurnal Farmasi dan Ilmu Kefarmasian Indonesia, 2020
Background: Epigallocatechin gallate (EGCG) is the most abundant green tea catechin with a powerful antioxidant effect to prevent cancer cells. EGCG in green tea solution is highly susceptible to degradation, this it is urgent to  increase the stability ...
Alief Putriana Rahman, Djoko Agus Purwanto, Isnaeni Isnaeni   +2 more
doaj   +1 more source

A Study of the Interaction, Morphology, and Structure in Trypsin-Epigallocatechin-3-Gallate Complexes

Molecules, 2021
Understanding the interaction between proteins and polyphenols is of significance to food industries. The aim of this research was to investigate the mode of aggregation for trypsin-EGCG (Epigallocatechin-3-gallate) complexes.
Jiayin Liu, Hossein Ghanizadeh, Xinmao Li, Zhengyuan Han, Youwen Qiu, Yao Zhang, Xiuling Chen, Aoxue Wang   +7 more
doaj   +1 more source

Camellia sinensis with its active compound EGCG can decrease necroptosis via inhibition of HO-1 expression [PDF]

, 2020
Stroke is the most common neurological disorder in the word. During ischemic stroke there is increasing of oxidative stress. Green tea (Camellia sinensis) have antioxidant and free radical scavenger effect. In vivo study using male Rattus Novergicus with
Imam Susilo, Budi Utomo, Paulus Sugianto, Imam Subadi, Djoko Agus Purwanto, Afif Nurul Hidayati, Abdulloh Machin, Aulanni'am, Chrismawan Ardianto, Nasronudin   +9 more
core