Results 81 to 90 of about 741,060 (264)

EGFR exon 19 in-frame deletion and polymorphisms of DNA repair genes in never-smoking female lung adenocarcinoma patients

, 2014
We explored potential associations between genetic polymorphisms in genes related to DNA repair and detoxification metabolism and epidermal growth factor receptor (EGFR) mutations in a cohort of 410 never-smoking patients with lung adenocarcinoma ...
Yang, Shi-Yi;Yang, Tsung-Ying;Li, Yao-Jen;Chen, Kun-Chieh;Liao, Kuo-Meng;Hsu, Kuo-Hsuan;Tsai, Chi-Ren;Chen, Chih-Yi;Hsu, Chung-Ping;Hsia, Jiun-Yi;Chuang, Cheng-Yen;Tsai, Ying-Huang;Chen, Kuan-Yu;Huang, Ming-Shyan;Su, Wu-Chou;Chen, Yuh-Min;Hsiung, Chao A.;Shen, Chen-Yang;Chang, Gee-Chen;Yang, Pan-Chyr;Chen, Chien-Jen, 陳建仁 ;楊泮池 ;陳冠宇   +1 more
core  

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

IMS chromatogram in patients with lung adenocarcinoma positive for EGFR mutation (A) and negative for EGFR mutation (B).

, 2014
IMS chromatogram in patients with lung adenocarcinoma positive for EGFR mutation (A) and negative for EGFR mutation (B).
Sasidhar Maddula (671901), Teruomi Miyazawa (617312), Hiroshi Handa (7692), Jörg Ingo Baumbach (671902), Ayano Usuba (671900), Masamichi Mineshita (617309)   +5 more
core   +1 more source

Clinical Impact of MGMT Promoter Methylation in IDH‐Mutant Gliomas: Influence of Threshold Selection and Clinical Confounding

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background The clinical relevance of MGMT promoter methylation in IDH‐mutant gliomas remains controversial in the era of molecular classification. We aimed to systematically evaluate its clinical relevance by integrating quantitative assessment, cutoff exploration, and adjustment for clinical confounding.
Haihui Jiang, Linxi Cao, Xiaodong Chen, Siqi Tong, Qinghui Zhu, Jun Yang, Song Lin, Yong Cui   +7 more
wiley   +1 more source

Prognostic analysis of patients with mutant and wild-type EGFR gene lung adenocarcinoma

Cancer Management and Research, 2019
Hongmei Zheng, Yuting Zhang, Yuting Zhan, Sile Liu, Junmi Lu, Juan Feng, Xia Wu, Qiuyuan Wen, Songqing FanDepartment of Pathology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, People’s Republic of ChinaPurpose: The
Zheng H, Zhang Y, Zhan Y, Liu S, Lu J, Feng J, Wu X, Wen Q, Fan S   +8 more
doaj  

Frequency of EGFR Mutations and Associated Clinical Factors in Thai Patients with Non-small Cell Lung Cancer (NSCLC)

Biomedical Sciences and Clinical Medicine
Objective Understanding clinical factors related to epidermal growth factor receptor (EGFR) mutation in lung cancer patients is imperative for effective treatment planning. It is also crucial to recognize ethnic differences.
Chaichana Chantharakhit, Wanfasai Chantharapha, Suwijak Teeramit, Tanyanat Kongket, Apichaya Wanwaisart, Poonyisa Praevijitr, Oratai Wongsuwan, Savita Puttipaisal   +7 more
doaj   +1 more source

Clinical impact of pleural fluid carcinoembryonic antigen on therapeutic strategy and efficacy in lung adenocarcinoma patients with malignant pleural effusion [PDF]

The Korean Journal of Internal Medicine
Background/Aims Epidermal growth factor receptor (EGFR) mutation is important in determining the treatment strategy for advanced lung cancer patients with malignant pleural effusion (MPE).
Jaehee Lee, Deok Heon Lee, Ji Eun Park, Yong Hoon Lee, Sun Ha Choi, Hyewon Seo, Seung Soo Yoo, Shin Yup Lee, Seung-Ick Cha, Jae Yong Park, Chang Ho Kim   +10 more
doaj   +1 more source

Combination of EGFR-TKIs with chemotherapy versus chemotherapy or EGFR-TKIs alone in advanced NSCLC patients with EGFR mutation

, 2018
Miaomiao Wen,1 Jinghua Xia,1 Ying Sun,1 Xuejiao Wang,1 Xianghui Fu,2 Yanning Zhang,1 Zhipei Zhang,1 Yongan Zhou,1 Xiaofei Li1 1Department of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi’an 710038, Shaanxi, China ...
Li X, Xia J, Wen M, Zhang Z, Fu X, Zhang Y, Wang X, Zhou Y, Sun Y   +8 more
core  

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj, Xilal Y. Rima, Kim T. Nguyen, Courtney Culkins, Nana Boateng, Jacob Doon‐Ralls, Alejandro Bresolin, Xin Huang, Hong Li, Vahedi Amid, Ajeet Pal Singh, Dharti Shantaram, Anastasiia Amari, Mangesh D. Hade, Nicholas R. Merriam, Zachary D. Schultz, Scott Q. Harper, Nizar Y. Saad, Setty M. Magaña, Willa A. Hsueh, Rachel E. Kopec, Blaise R. Kimmel, Andre F. Palmer, Eduardo Reátegui   +23 more
wiley   +1 more source

Outcome of uncommon EGFR mutation positive newly diagnosed advanced non-small cell lung cancer patients: a single center retrospective analysis

, 2019
Shruti Kate,1 Anuradha Chougule,2 Amit Joshi,1 Vanita Noronha,1 Vijay Patil,1 Rohit Dusane,3 Leena Solanki,1 Priyanka Tiwrekar,2 Vaishakhi Trivedi,1 Kumar Prabhash1 1Department of Medical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India ...
Patil V, Tiwrekar P, Kate S, Chougule A, Noronha V, Trivedi V, Dusane R, Prabhash K, Joshi A, Solanki L   +9 more
core