Results 61 to 70 of about 106,112 (199)

Rapamycin Alleviates Heart Failure Caused by Mitochondrial Dysfunction and SERCA Hypoactivity in Syntaxin 12/13 Deficient Models

open access: yesAdvanced Science, EarlyView.
Rapamycin alleviates heart failure via TFEB and CaMKII pathways in Syntaxin 12/13 deficient models. Stx12 deficiency causes heart failure via impaired iron trafficking to mitochondria, reducing respiratory complexes and sarcoplasmic reticulum Ca2+‐ATPase (SERCA).
Run‐Zhou Yang   +12 more
wiley   +1 more source

Hologenomics Reveals Specialized Dietary Adaptations in the Mengla Snail‐Eating Snake

open access: yesAdvanced Science, EarlyView.
Dietary adaptation studies from a holobiome perspective are scarce beyond mammals. This research reveals how genomic and microbial interactions drive dietary specialization in the Mengla snail‐eating snake, with evidence of gut symbiont convergence between reptiles and mammals.
Chaochao Yan   +10 more
wiley   +1 more source

Are PM6:Y6 Bulk Heterojunction Photoactive Films Cytocompatible and Electrically Stable in Biological Environments?

open access: yesAdvanced Electronic Materials, EarlyView.
PM6:Y6 organic photovoltaic films are systematically studied to understand their potential for use in bioelectronics. The films exhibit excellent stability in simulated physiological environments, enabling consistent power delivery and demonstrating compatibility with rat neurons and the choriallantoic membrane of chicken embryos.
Mathias Polz   +10 more
wiley   +1 more source

Incorporating economic multipliers in a bid adjustment algorithm for public food procurement decision making

open access: yesApplied Economic Perspectives and Policy, EarlyView.
Abstract We present an adjusted bid price mechanism that incorporates economic multiplier effects in public food procurement decision making. Under Input–Output model assumptions, the algorithm estimates enhanced tax revenues to state governments through multiplier effects associated with in‐state supplier purchasing.
Todd M. Schmit, Xiaoyan Liu
wiley   +1 more source

Relationship of Candled Quality of Eggs to Other Quality Measurements

open access: hybrid, 1953
E.A. Sauter   +3 more
openalex   +1 more source

What matters for agricultural trade? Assessing the role of trade deal provisions using machine learning

open access: yesApplied Economic Perspectives and Policy, EarlyView.
Abstract This paper employs machine learning to determine which preferential trade agreement (PTA) provisions are relevant to agricultural trade patterns and the factors that may influence their adoption. Utilizing the three‐way gravity model, we apply plug‐in Lasso regularized regression to pinpoint predictive PTA provisions for agricultural trade ...
Stepan Gordeev   +3 more
wiley   +1 more source

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