Results 111 to 120 of about 385,324 (188)

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

The Chicken Egg Genotoxicity Assay (CEGA): Assessing Target Tissue Exposure and Metabolism in the Embryo‐Fetal Chicken Livers

Environmental and Molecular Mutagenesis, EarlyView.
ABSTRACT The Chicken Egg Genotoxicity Assay (CEGA) is an avian egg‐based model that utilizes the livers of developing chicken embryo‐fetuses to assess the ability of chemicals to produce direct DNA damage. The main goal of the study was to evaluate target tissue exposure and metabolism in the CEGA to assess its suitability as a biologically relevant ...
Yax Thakkar, T. Kobets, Anne Marie Api, J. D. Duan, G. M. Williams   +4 more
wiley   +1 more source

The Prevalence of Excessive Exercise in Eating Disorders: A Systematic Review and Meta‐Analysis

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Individuals with eating disorders (EDs) often present with maladaptive behaviours such as excessive exercise (EE). The consequences of EE include physical injuries, increased risk of anxiety and depression, and impaired social functioning. No systematic reviews have been conducted on the prevalence of EE in EDs.
Connor Campbell, Xander Greig, Jessica Griffiths, Devon Hashman, Thomas Sottile, Masanori Isobe, Anees Bahji, Gina Dimitropoulos, Dan Devoe   +8 more
wiley   +1 more source

Contextualising Physical Activity Levels in Patients With Anorexia Nervosa: A Systematic Review and Meta‐Analysis

European Eating Disorders Review, EarlyView.
ABSTRACT Background and objective Anorexia nervosa (AN) is a mental disorder most prevalent among adolescent females, with rising cases in younger and more culturally diverse populations. Unhealthy activity patterns are common and have been linked to increased relapse rates; however, data on objectively measured physical activity levels (PALs) in this ...
Álex V. Pagador, Hugo Olmedillas, Danika A. Quesnel, Iván Cavero‐Redondo, María Fernandez‐del‐Valle   +4 more
wiley   +1 more source

Inconsistent Transcriptomic Responses to Hexabromocyclododecane in Japanese Quail: A Comparative Analysis of Results From Four Different Study Designs

Environmental Toxicology and Chemistry, EarlyView.
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers, Elena Legrand, Emily Boulanger, Niladri Basu, Jessica D. Ewald, Paula Henry, Markus Hecker, Jianguo Xia, Natalie Karouna‐Renier, Doug Crump, Jessica Head   +10 more
wiley   +1 more source

Use of Liquid Nitrogen in Food Products: A Review

Food Frontiers, EarlyView.
ABSTRACT The increasing demand for frozen products has led companies to offer a variety of foods that may struggle to maintain quality. Traditional freezing methods often negatively impact food quality, affecting texture, color, flavor, and so forth.
Fabiola Pesce, Lucia Parafati, Biagio Fallico, Rosa Palmeri   +3 more
wiley   +1 more source

Actinidia spp. (Kiwifruit): A Comprehensive Review of Its Nutraceutical Potential in Disease Mitigation and Health Enhancement

Food Frontiers, EarlyView.
Nutraceutical Potential in Disease Mitigation and Health Enhancement of Actinidia spp. (Kiwifruit) ABSTRACT This review offers an in‐depth exploration of the Actinidia species (kiwifruit) nutritional composition, the pivotal role of its primary bioactive compounds, and their potential applications across the aforementioned health concerns. Furthermore,
Allah Rakha, Nida Rehman, Rimsha Anwar, Hina Rasheed, Roshina Rabail, Zuhaib F. Bhat, Amin Mousavi Khaneghah, Rana Muhammad Aadil   +7 more
wiley   +1 more source

The Postbiotic Potential of Microalgae

Food Frontiers, EarlyView.
Description of “Microalgal Postbiotic” following ISAPP Consensus (Salminen et al. 2021b) (Icons produced with Biorender) ABSTRACT The International Scientific Association for Probiotics and Prebiotics (ISAPP) has defined postbiotics as “preparations of inanimate microorganisms and/or their components that confer a health benefit on the host ...
Francesco Martelli, Caterina Nicolotti, Benedetta Bottari   +2 more
wiley   +1 more source

Isolation and Extraction of Gentian Polysaccharide and Its Protective Effect on Chemical Liver Injury

Food Safety and Health, EarlyView.
The water‐soluble polysaccharide GSBP‐N‐a‐1 with an average molecular weight of 3.82 kDa was successfully isolated and purified from Gentiana scabra. It was confirmed that the crude polysaccharides of Gentiana scabra could inhibit oxidative stress and inflammatory response by activating the Nrf2‐HO‐1 pathway, and significantly alleviate the chemical ...
Tianjiao Fu, Yan Dong, Guangxin Yuan
wiley   +1 more source

Phytochemical Contents and Bioactive Compounds in Widely Consumed Cereals, Legumes, and Vegetables in Abruzzo Region, Italy: A Critical Review

Food Safety and Health, EarlyView.
This review aims to collect and identify cereals, legumes, and vegetables mostly consumed in the Abruzzo region from 2020 till now, pointing attention to their biological effects. ABSTRACT The Abruzzo region boasts a wide range of typical food products including cereals, legumes, and vegetables. In this context, they take part in the Mediterranean diet,
Giulia Gentile, Lorenza Marinaccio, Adriano Mollica, Azzurra Stefanucci   +3 more
wiley   +1 more source