Novel Coumarin Derivatives with Expected Biological Activity
A number of novel 3-bromo-4-methyl-7-methoxy-8-amino substituted coumarins and 2-substituted 7-bromo-6-methyl-8H-pyrano-benzimidazoles, benzoxazoles and/or benzoxazine-8-ones were synthesized for the purpose of pharmacological evaluation.
S. S. Abd El-Karim +2 more
doaj +1 more source
EVALUATION OF APOPTOGENIC EFFECTS OF AVERRHOA BILIMBI EXTRACT ON EHRLICH ASCITES CARCINOMA BEARING MICE [PDF]
Objective: The proapoptotic potential of aqueous methanol extract of Averrhoa bilimbi fruit (AMBE) in vivo against Ehrlich ascites carcinoma (EAC)bearing Swiss albino mice was studied.Methods: Cytotoxicity of the extract on the EAC cells was monitored by
S, Jayarama +3 more
core +3 more sources
This graphical abstract illustrates the complete translational pipeline of Terminalia arjuna in modern phytomedicine and functional food development. It is rich in key bioactive compounds like arjunolic acid, arjungenin, flavonoids, and tannins which serve as the foundation for the plant's versatile medicinal uses and offers broad therapeutic benefits ...
Ishani Banerjee +5 more
wiley +1 more source
Antitumor and structure antioxidant activity relationship of Colchicine on Ehrlich ascites Carcinoma (EAC) in Female Mice [PDF]
Colchicine has been reported to play important roles in hepatoprotection, anti-inflammation in vitro anti cancer activity. The present study was initiated to evaluate antioxidant and anti-cancer effects of colchicine (10µg/mice, i.p.) in mice after ...
Boshra, Sylvia A; Biochemistry Department, Faculty of Pharmacy, October 6 University, 6th October city, Egypt +1 more
core +2 more sources
Mesothelin as Biomarker and Therapeutic Target for Immunotherapy in Cancer
Mesothelin overexpression activate important pathways like nuclear factor k‐light‐chain‐enhancer of activated B cells (NF‐κB) and interleukin‐6 (IL‐6). This in turn causes numerous cancers, such as pancreatic and ovarian cancers. MSLN‐targeting immunotherapies, like monoclonal antibodies, have shown efficacy.
Manoj Kumar Gupta +2 more
wiley +1 more source
In vivo Efficacy of HIFU (High Intensity Focused Ultrasound) on Mice with Ehrlich Ascites Carcinoma
Objective:Cavitation and coagulation necrosis due to high temperature caused by application of the high intensity focused ultrasound (HIFU) to a focal area occurs. This feature makes HIFU possible to use in the destruction of cancerous tissue.
Mustafa HASBAHÇECİ +7 more
doaj +1 more source
Phosphorylation of choline and ethanolamine in Ehrlich ascites-carcinoma cells [PDF]
1. Ehrlich ascites-cell extracts convert choline and ethanolamine approximately equally well into their respective phosphoryl derivatives. 2. Choline is a potent inhibitor of ethanolamine phosphorylation, but ethanolamine has little effect on choline phosphorylation. 3. 2,3-Dimercaptopropanol, cysteine and Ca2+ inhibit ethanolamine phosphorylation, but
C P, Sung, R M, Johnstone
openaire +2 more sources
Cinnamaldehyde derived from Cinnamomum species exerts multitarget anticancer effects by promoting oxidative stress, mitochondrial dysfunction, apoptosis, cell‐cycle arrest, autophagy, and epigenetic changes, and by suppressing mitogen‐activated protein kinase (MAPK), phosphoinositide 3‐kinase/protein kinase B/mechanistic target of rapamycin (PI3K/Akt ...
Gervason Moriasi +6 more
wiley +1 more source
Studies on the treatment of malignant tumors with fibroblast-inhibiting agents Part Ⅲ. Effects of chloroquine on tumor-bearing animals (Ehrlich ascites carcinoma and MH 134 ascites hepatoma) [PDF]
Effects of fibroblast-inhibiting chloroquine diphosphate on ascites tumors such as Ehrlich ascites carcinoma and MH 134 ascites hepatoma weres tudied and the following results were obtained.
Shibuya, Koichi
core
Pathophysiology of elevated ascites fluid cholesterol in malignant ascites [PDF]
The existence of marked elevations of ascitic fluid cholesterol has been observed in patients with peritoneal carcinomatosis compared to patients with cirrhosis and has been found useful in differential diagnosis.
Jüngst, Dieter +2 more
core +1 more source

