Results 51 to 60 of about 5,798 (217)

Exploring the Cancer Therapeutic Potential of Traditional Medicinal Plants by Modulating the Apoptotic Pathway

BioMed Research International, Volume 2026, Issue 1, 2026.
Introduction Cancer is a versatile disease with a high rate of relapse and mortality. Despite the presence of various treatment modalities, there is a serious need for the development of its management. Phytochemicals, which are abundant in nature, can be turned into novel medications for these types of diseases by optimizing their functions and ...
Mithila Kulkarni, Mohammad Amjad Hussain, Reginald Samson Valdar, Shreya Hebbar, Suparna Laha, Poorani Gurumallesh Prabu   +5 more
wiley   +1 more source

Methanolic extract of moringa oleifera leaves mediates anticancer activities through inhibiting nf-ĸb and enhancing ros in ehrlich ascites carcinoma cells in mice

, 2021
Cancer is one of the vital causes of morbidity and mortality worldwide and recognized as the second most leading cause of death. Considering the side effects and high cost of synthetic anticancer drugs, plant might act as a source of novel anticancer ...
Islam, F, Das, PK, Rakib, MA, Siddika, MA, Siddika, A, M Tareq, AR, Asha, SY, Khanam, JA   +7 more
core   +1 more source

EVALUATION OF APOPTOGENIC EFFECTS OF AVERRHOA BILIMBI EXTRACT ON EHRLICH ASCITES CARCINOMA BEARING MICE

, 2016
Objective: The proapoptotic potential of aqueous methanol extract of Averrhoa bilimbi fruit (AMBE) in vivo against Ehrlich ascites carcinoma (EAC)bearing Swiss albino mice was studied.Methods: Cytotoxicity of the extract on the EAC cells was monitored by
K S Balaji, Wethroe Kapfo, S Jayarama, Jyoti Bala Chauhan   +3 more
core   +2 more sources

Cyclosporin A corrects daunorubicin resistance in Ehrlich ascites carcinoma [PDF]

British Journal of Cancer, 1986
We have previously developed a daunorubicin resistant subline of Ehrlich ascites carcinoma (EA/DR) for studies on the reversal of daunorubicin resistance. The mean survival of untreated BALB/c mice bearing drug sensitive parental tumour (EA/DS) is 18.4 +/- 0.6 days, mice bearing EA/DS treated with five daily doses of 0.3 mg kg-1 daunorubicin greater ...
Slater, LM, Sweet, P, Stupecky, M, Wetzel, MW, Gupta, S   +4 more
openaire   +4 more sources

Health Benefits and Therapeutic Potential of Quercetin

Journal of Food Biochemistry, Volume 2026, Issue 1, 2026.
Quercetin, a polyphenolic compound prevalent in many fruits, vegetables, and other dietary sources, has attracted considerable interest due to its extensive health benefits. This review examines its diverse biological properties, particularly its antioxidant and anti‐inflammatory effects. The study integrates recent scientific findings to elucidate the
Mahendra Aryal, Kim Wei Chan
wiley   +1 more source

Possible anticancer effects of rutin and orlistat in Ehrlich-ascites carcinoma in mice

Zagazig Journal of Pharmaceutical Sciences, 2017
Cancer is a broad term used to describe a large number of diseases characterized by uncontrolled cell proliferation that leads to tumor production.
Amira Saleh, Hassan M. ELFayoumi , Waleed Barakat   +2 more
doaj   +1 more source

Phytochemical Profiling and Computational Docking Studies Revealing the Potential Anticancer and Antioxidant Properties of Heliotropium indicum L.

Scientifica, Volume 2026, Issue 1, 2026.
This study explores the anticancer and antioxidant potential of Heliotropium indicum L. through integrated phytochemical, biological, and computational approaches. GC–MS analysis identified phenol, 3,5‐bis(1,1‐dimethylethyl) as a major constituent. The chloroform fraction (CHF) exhibited significant in vivo antitumor activity in an Ehrlich ascites ...
Sadia Afroz Shoily, Mst. Shahnaj Parvin, Mohsin Kazi, Aqibul Hasan Aqib, Md. Sabbir Hossain, Rasel Ahmed, Rafat Hossain Rafi, Jaytirmoy Barmon, Mohammad N. Uddin, Md. Ekramul Islam, Muhammad Iqhrammullah   +10 more
wiley   +1 more source

Flaxseed Ethanol Extracts’ Antitumor, Antioxidant, and Anti-Inflammatory Potential

Antioxidants, 2022
The antitumoral, antioxidant, and anti-inflammatory effects of flaxseed ethanol extract was screened. Phytochemical analysis was performed by measuring the total phenolic content and by HPLC-DAD-ESI MS. In vitro antiproliferative activity was appreciated
Elisabeta Ioana Chera, Raluca Maria Pop, Marcel Pârvu, Olga Sorițău, Ana Uifălean, Florinela Adriana Cătoi, Andra Cecan, Andrada Gabriela Negoescu, Patriciu Achimaș-Cadariu, Alina Elena Pârvu   +9 more
doaj   +1 more source

Polysaccharide Adjuvants as Innate Immune Trainers: Bridging Pattern Recognition Receptor (PRR) Activation and Metabolic Reprogramming for Synthetic Vaccine Design

Advanced Science, Volume 12, Issue 48, December 29, 2025.
Polysaccharides modulate immune responses by engaging pattern recognition receptors (PRRs) to induce T‐cell activation. In vaccine design, their particle size critically influences lymph node targeting and activation mechanisms. By engineering structural complexity and multivalent PRR engagement, polysaccharides enable precise modulation of immune ...
Jeong Hyun Moon, May Thazin Phoo, Yubin Kim, Jinsung Ahn, April Kim, Jutaek Nam, Soo‐Hong Lee, James J. Moon, Sejin Son   +8 more
wiley   +1 more source

2, 4-dihydroxy-3, 4-methylenedioxychalcone activate mitochondrial apoptosis of Ehrlich ascites carcinoma cells

, 2019
Background: Development of effective cancer-chemotherapy is the most challenging field due to toxicity of chemo-agents. Objective: As chalcone has been known to have pharmacological applications, here we aimed to synthesized three chalcone derivatives, 2'
Lam, Alfred King-Yin, Gopalan, Vinod, Khatun, Laboni, Khanam, Jahan Ara, Khatun, Mahbuba, Islam, Farhadul, Zuberi, Natasha, Rahman, Md Motiar, Rakiba, Md Abdur, Islam, Md Azizul   +9 more
core   +1 more source