Results 41 to 50 of about 12,087 (179)
Integrative Zoology, EarlyView.Kaempferol modulates the tryptophan metabolism pathway by increasing the abundances of Christensenellaceae R7 group, Bacteroides, and Blautia and reducing that of Rikenellaceae RC9 gut group, thereby significantly increasing the levels of ILA and IAA. This process inhibits the activation of NF‐κB/NLRP3 signaling pathway, reduces pro‐inflammatory factor
Xiangyu Liu +3 more
wiley +1 more source
The Therapeutic Potential of Farm Dust Extracts in a Mouse Model of Eosinophilic Inflammation
Allergy, EarlyView.Farm dust extract (FDE) treatment reduces airway eosinophilia, mucus overproduction, and MHC‐II expression on DCs, limiting antigen presentation and Th2 inflammation. It increases PD‐L1 on DCs, promoting T cell deactivation. Additionally, FDE enhances Tregs and upregulates CTLA‐4, reinforcing suppression.
Rabia Ülkü Korkmaz +16 more
wiley +1 more source
Antitumor effect of lysine-isopeptides
Cancer Cell International, 2002 Isopeptides (ε-peptides) of lysine, with a given Mw and low polydispersity (10–400 units), were synthesized to study the relationship between their chemical structure and biological effect.
Gáborjányi R +6 more
doaj +1 more source
Induction of IL‐9‐producing CD8+ T cells by ascochlorin derivatives
British Journal of Pharmacology, EarlyView.A newly synthesised ascochlorin derivative, N184, induces small amounts of IL‐9‐producing CD8+ T cells. N184 improved the survival of CD8+ T cells and enhanced their antitumour activity, partially in an IL‐9‐dependent manner. The antitumour effect was completely dependent on IFNγ secretion rather than the cytotoxic activity of CD8+ T cells.
Natsumi Imano +5 more
wiley +1 more source
Antibiotic‐mediated immune modulation in periodontitis
Periodontology 2000, EarlyView.Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez +6 more
wiley +1 more source
The anticancer activity of dichloromethane crude extract obtained from Calea pinnatifida
Journal of Experimental Pharmacology, 2012 Gabriela M Marchetti,1,2 Karina A Silva,3 Arianny N Santos,3 Ilza MO Sousa,3 Sirlene V Tinti,2 Glyn M Figueira,4 Mary A Foglio,1,3 João E Carvalho1,21Programa de Pós Graduação em Biologia Celular e Estrutural ...
Foglio MA +7 more
doaj
Mimosine and cyclophosphamide: a potential new combination therapy used to prevent tumor development
Brazilian Archives of Biology and Technology, 2012 The effects of mimosine (MI), which is an amino acid that is derived from Leucaena leucocephala, were evaluated on the growth of ascitic Ehrlich tumors, and the effects of the combination treatment of MI and cyclophosphamide (CY) on tumor growth were ...
Vânius Vinícius Dipe +3 more
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Vox Sanguinis, EarlyView.Abstract Background and Objectives Ageing populations in high‐income countries reduce the proportion of potential blood donors while increasing transfusion demand. Sustaining an adequate blood supply requires higher donor motivation among younger age groups.
Sophia Oesterreicher +8 more
wiley +1 more source
In vivo Efficacy of HIFU (High Intensity Focused Ultrasound) on Mice with Ehrlich Ascites Carcinoma
Bezmiâlem Science, 2017 Objective:Cavitation and coagulation necrosis due to high temperature caused by application of the high intensity focused ultrasound (HIFU) to a focal area occurs. This feature makes HIFU possible to use in the destruction of cancerous tissue.
Mustafa HASBAHÇECİ +7 more
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Memorias do Instituto Oswaldo Cruz, 1973 The perchloro-soluble mucroptotein fraction was determined in the cells of Ehrlich ascites carcinoma on the 10th and 12th days post-inoculation of the tumor.
R. Raposo Abreu, Luiz A. Abreu
doaj +1 more source