Human Case of Ehrlichia chaffeensis Infection, Taiwan [PDF]
Emerging Infectious Diseases, 2019 In 2018, an immunosuppressed woman in southern Taiwan had onset of fever, chills, myalgia, malaise, thrombocytopenia, lymphocytopenia, and elevated hepatic transaminases. Investigation revealed infection with Ehrlichia chaffeensis.
Shih-Huan Peng +4 more
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Ehrlichia chaffeensis Co-Opts Phagocytic Hemocytes for Systemic Dissemination in the Lone Star Tick, Amblyomma americanum [PDF]
Journal of Innate Immunity, 2023 Introduction: Hematophagous arthropods can acquire and transmit several pathogens of medical importance. In ticks, the innate immune system is crucial in the outcome between vector-pathogen interaction and overall vector competence. However, the specific
Abdulsalam Adegoke +3 more
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Antibody reactive immunomes of Ehrlichia chaffeensis and E. canis are diverse and defined by conformational antigenic determinants [PDF]
Frontiers in Cellular and Infection Microbiology, 2023 For decades, the defined antibody reactive proteins of Ehrlichia chaffeensis and E. canis were limited to a small group with linear antibody epitopes.
Tian Luo +7 more
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Efficacy and Immune Correlates of OMP-1B and VirB2-4 Vaccines for Protection of Dogs from Tick Transmission of Ehrlichia chaffeensis [PDF]
mBio, 2022 Ehrlichia chaffeensis, an obligatory intracellular bacterium, causes human monocytic ehrlichiosis, an emerging disease transmitted by the Lone Star tick, Amblyomma americanum. Here, we investigated the vaccine potential of OMP-1B and VirB2-4.
Khemraj Budachetri +5 more
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Glutathione Synthesis Regulated by CtrA Protects Ehrlichia chaffeensis From Host Cell Oxidative Stress [PDF]
Frontiers in Microbiology, 2022 Ehrlichia chaffeensis, a small Gram-negative obligatory intracellular bacterium, infects human monocytes or macrophages, and causes human monocytic ehrlichiosis, one of the most prevalent, life-threatening emerging zoonoses.
Jiaqi Yan +11 more
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The “Biological Weapons” of Ehrlichia chaffeensis: Novel Molecules and Mechanisms to Subjugate Host Cells [PDF]
Frontiers in Cellular and Infection Microbiology, 2022 Ehrlichia chaffeensis is an obligatory intracellular bacterium that causes human monocytic ehrlichiosis, an emerging, potentially fatal tick-borne infectious disease.
Yasuko Rikihisa
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Ehrlichia chaffeensis Infection of Sika Deer, Japan
Emerging Infectious Diseases, 2009 To determine whether Ehrlichia chaffeensis exists in Japan, we used PCR to examine blood from sika deer in Nara, Japan. Of 117 deer, 36 (31%) were infected with E. chaffeensis. The E.
Makoto Kawahara +7 more
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CtrA activates the expression of glutathione S-transferase conferring oxidative stress resistance to Ehrlichia chaffeensis [PDF]
Frontiers in Cellular and Infection Microbiology, 2022 Ehrlichia chaffeensis, the causative agent of human monocytic ehrlichiosis (HME), is a Gram-negative obligatory intracellular bacterium, which infects and multiplies in human monocytes and macrophages.
Qi’an Liang +8 more
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Hacker Within! Ehrlichia chaffeensis Effector Driven Phagocyte Reprogramming Strategy [PDF]
Frontiers in Cellular and Infection Microbiology, 2016 Ehrlichia chaffeensis is a small, gram negative, obligately intracellular bacterium that preferentially infects mononuclear phagocytes. It is the etiologic agent of human monocytotropic ehrlichiosis (HME), an emerging life-threatening tick-borne zoonosis.
Taslima Taher Lina +5 more
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mBio, 2020 The obligatory intracellular pathogen Ehrlichia chaffeensis lacks most factors that could respond to oxidative stress (a host cell defense mechanism).
Omid Teymournejad, Yasuko Rikihisa
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